[HTML][HTML] MicroRNA amplification and detection technologies: opportunities and challenges for point of care diagnostics

VP Dave, TA Ngo, AK Pernestig, D Tilevik, K Kant… - Laboratory …, 2019 - Elsevier
The volume of point of care (POC) testing continues to grow steadily due to the increased
availability of easy-to-use devices, thus making it possible to deliver less costly care closer …

miRNA assays in the clinical laboratory: workflow, detection technologies and automation aspects

A Kappel, A Keller - Clinical Chemistry and Laboratory Medicine …, 2017 - degruyter.com
Abstract microRNAs (miRNAs) are short non-coding RNA molecules that regulate gene
expression in eukaryotes. Their differential abundance is indicative or even causative for a …

Detection methods for microRNAs in clinic practice

M de Planell-Saguer, MC Rodicio - Clinical biochemistry, 2013 - Elsevier
MicroRNAs (miRNA) are short non-coding RNA molecules that regulate gene expression.
miRNAs profiles are specific for cell lineages and tissues, and their changes reflect …

MicroRNA detection: current technology and research strategies

EA Hunt, D Broyles, T Head… - Annual review of analytical …, 2015 - annualreviews.org
The relatively new field of microRNA (miR) has experienced rapid growth in methodology
associated with its detection and bioanalysis as well as with its role in-omics research …

Trends in microRNA detection

KA Cissell, SK Deo - Analytical and bioanalytical chemistry, 2009 - Springer
Abstract MicroRNAs (miRNAs) are short,~ 22 nucleotide length RNAs that perform gene
regulation. Recently, miRNA has been shown to be linked with the onset of cancer and other …

Emerging isothermal amplification technologies for microRNA biosensing: Applications to liquid biopsies

G Gines, R Menezes, W Xiao, Y Rondelez… - Molecular Aspects of …, 2020 - Elsevier
The potential of microRNAs (miRNAs) as biomarker candidates in clinical practice for
diagnosis, prognosis and treatment response prediction, especially in liquid biopsies, has …

Defining quantification methods and optimizing protocols for microarray hybridization of circulating microRNAs

A Garcia-Elias, L Alloza, E Puigdecanet, L Nonell… - Scientific reports, 2017 - nature.com
MicroRNAs (miRNAs) have emerged as promising biomarkers of disease. Their potential
use in clinical practice requires standardized protocols with very low miRNA concentrations …

Recent advances in microRNA detection

Y Cheng, L Dong, J Zhang, Y Zhao, Z Li - Analyst, 2018 - pubs.rsc.org
The development of simple, robust, and reliable microRNA (miRNA) detection methods is of
great significance in the studies of the biological function of miRNAs, molecular diagnostics …

Evaluation of methodologies for microRNA biomarker detection by next generation sequencing

AML Coenen-Stass, I Magen, T Brooks, IZ Ben-Dov… - RNA biology, 2018 - Taylor & Francis
In recent years, microRNAs (miRNAs) in tissues and biofluids have emerged as a new class
of promising biomarkers for numerous diseases. Blood-based biomarkers are particularly …

MicroRNAs as biomarkers for clinical studies

IP Pogribny - Experimental Biology and Medicine, 2018 - journals.sagepub.com
The development of better diagnostic and prognostic non-invasive biomarkers holds an
enormous potential to improve the ability to diagnose and individualize treatment of a great …