[HTML][HTML] Predicting microRNA targeting efficacy in Drosophila

V Agarwal, AO Subtelny, P Thiru, I Ulitsky, DP Bartel - Genome biology, 2018 - Springer
Background MicroRNAs (miRNAs) are short regulatory RNAs that derive from hairpin
precursors. Important for understanding the functional roles of miRNAs is the ability to …

Conserved microRNA targeting in Drosophila is as widespread in coding regions as in 3′UTRs

M Schnall-Levin, Y Zhao… - Proceedings of the …, 2010 - National Acad Sciences
MicroRNAs (miRNAs) are a class of short noncoding RNAs that regulate protein-coding
genes posttranscriptionally. In animals, most known miRNA targeting occurs within the 3 …

Systematic discovery and characterization of fly microRNAs using 12 Drosophila genomes

A Stark, P Kheradpour, L Parts, J Brennecke… - Genome …, 2007 - genome.cshlp.org
MicroRNAs (miRNAs) are short regulatory RNAs that inhibit target genes by complementary
binding in 3′ untranslated regions (3′ UTRs). They are one of the most abundant classes …

Evolution, biogenesis, expression, and target predictions of a substantially expanded set of Drosophila microRNAs

JG Ruby, A Stark, WK Johnston, M Kellis… - Genome …, 2007 - genome.cshlp.org
MicroRNA (miRNA) genes give rise to small regulatory RNAs in a wide variety of organisms.
We used computational methods to predict miRNAs conserved among Drosophila species …

[HTML][HTML] microRNA Target Predictions across Seven Drosophila Species and Comparison to Mammalian Targets

D Grün, YL Wang, D Langenberger… - PLoS computational …, 2005 - journals.plos.org
microRNAs are small noncoding genes that regulate the protein production of genes by
binding to partially complementary sites in the mRNAs of targeted genes. Here, using our …

Deep conservation of microRNA-target relationships and 3'UTR motifs in vertebrates, flies, and nematodes

K Chen, N Rajewsky - Cold Spring Harbor symposia on …, 2006 - symposium.cshlp.org
Abstract microRNAs (miRNAs) are a class of small noncoding RNAs that
posttranscriptionally regulate a large fraction of genes inanimal genomes. We have …

[HTML][HTML] Identification of Drosophila microRNA targets

A Stark, J Brennecke, RB Russell, SM Cohen - PLoS biology, 2003 - journals.plos.org
MicroRNAs (miRNAs) are short RNA molecules that regulate gene expression by binding to
target messenger RNAs and by controlling protein production or causing RNA cleavage. To …

[HTML][HTML] Prediction of mammalian microRNA targets

BP Lewis, I Shih, MW Jones-Rhoades, DP Bartel… - Cell, 2003 - cell.com
MicroRNAs (miRNAs) can play important gene regulatory roles in nematodes, insects, and
plants by basepairing to mRNAs to specify posttranscriptional repression of these …

microRNA target predictions in animals

N Rajewsky - Nature genetics, 2006 - nature.com
In recent years, microRNAs (miRNAs) have emerged as a major class of regulatory genes,
present in most metazoans and important for a diverse range of biological functions …

A genome-wide transgenic resource for conditional expression of Drosophila microRNAs

F Bejarano, D Bortolamiol-Becet, Q Dai, K Sun… - …, 2012 - journals.biologists.com
microRNAs (miRNAs) are endogenous short RNAs that mediate vast networks of post-
transcriptional gene regulation. Although computational searches and experimental profiling …