Proteomics-based vaccine targets annotation and design of subunit and mRNA-based vaccines for Monkeypox virus (MPXV) against the recent outbreak

Y Jin, A Fayyaz, A Liaqat, A Khan, A Alshammari… - Computers in Biology …, 2023 - Elsevier
Monkeypox Virus (MPXV) is a growing public health threat with increasing cases and
fatalities globally. To date, no specific vaccine or small molecule therapeutic choices are …

Immunoinformatics design of multivalent epitope vaccine against monkeypox virus and its variants using membrane-bound, enveloped, and extracellular proteins as …

M Waqas, S Aziz, P Liò, Y Khan, A Ali, A Iqbal… - Frontiers in …, 2023 - frontiersin.org
Introduction The current monkeypox (MPX) outbreak, caused by the monkeypox virus
(MPXV), has turned into a global concern, with over 59,000 infection cases and 23 deaths …

Immunoinformatics-based multi-epitope vaccine design for the re-emerging monkeypox virus

M Farzan, M Farzan, Y Mirzaei, S Aiman… - International …, 2023 - Elsevier
Abstract Background On May 7, 2022, WHO reported a new monkeypox case. By May 2023
over 80,000 cases had been reported worldwide outside previously endemic nations.(This …

Immunoinformatic-guided novel mRNA vaccine designing to elicit immunogenic responses against the endemic Monkeypox virus

S Aiman, Y Ali, A Malik, M Alkholief… - Journal of …, 2023 - Taylor & Francis
Monkeypox virus (MPXV) is an orthopoxvirus, causing zoonotic infections in humans with
smallpox-like symptoms. The WHO reported MPXV cases in May 2022 and the outbreak …

Novel multi epitope-based vaccine against monkeypox virus: vaccinomic approach

SW Shantier, MI Mustafa, AH Abdelmoneim, HA Fadl… - Scientific Reports, 2022 - nature.com
While mankind is still dealing with the COVID-19 pandemic, a case of monkeypox virus
(MPXV) has been reported to the WHO on May 7, 2022. Monkeypox is a viral zoonotic …

[HTML][HTML] Contriving multi-epitope vaccine ensemble for monkeypox disease using an immunoinformatics approach

S Aziz, FN Almajhdi, M Waqas, I Ullah… - Frontiers in …, 2022 - frontiersin.org
The current global outbreak of monkeypox (MPX) disease, caused by Monkeypox virus
(MPXV), has resulted in 16 thousand infection cases, five deaths, and has been declared a …

Immunoinformatics-aided design of a peptide based multiepitope vaccine targeting glycoproteins and membrane proteins against monkeypox virus

N Akhtar, V Kaushik, RK Grewal, AK Wani… - Viruses, 2022 - mdpi.com
Monkeypox is a self-limiting zoonotic viral disease and causes smallpox-like symptoms. The
disease has a case fatality ratio of 3–6% and, recently, a multi-country outbreak of the …

In silico design and immunoinformatics analysis of a universal multi-epitope vaccine against monkeypox virus

S Sanami, S Nazarian, S Ahmad, E Raeisi… - PLoS …, 2023 - journals.plos.org
Monkeypox virus (MPXV) outbreaks have been reported in various countries worldwide;
however, there is no specific vaccine against MPXV. In this study, therefore, we employed …

[HTML][HTML] Development of multi-epitope vaccines against the monkeypox virus based on envelope proteins using immunoinformatics approaches

C Tan, F Zhu, P Pan, A Wu, C Li - Frontiers in Immunology, 2023 - frontiersin.org
Background Since May 2022, cases of monkeypox, a zoonotic disease caused by the
monkeypox virus (MPXV), have been increasingly reported worldwide. There are, however …

[HTML][HTML] Multi-epitope chimeric vaccine design against emerging Monkeypox virus via reverse vaccinology techniques- a bioinformatics and immunoinformatics …

S Aiman, Y Alhamhoom, F Ali, N Rahman… - Frontiers in …, 2022 - frontiersin.org
The emerging monkeypox virus (MPXV) is a zoonotic orthopoxvirus that causes infections in
humans similar to smallpox. Since May 2022, cases of monkeypox (MPX) have been …