“Green” synthesized versus chemically synthesized zinc oxide nanoparticles: In vivo antihyperglycemic activity and pharmacokinetics

EK Kambale, I Domingues, W Zhang, V Marotti… - International journal of …, 2024 - Elsevier
Zinc is one of the most studied trace elements, commonly used as supplement in diabetes
treatment. By its involvement in the synthesis, secretion of insulin, promotion of insulin …

“Green”-synthesized zinc oxide nanoparticles and plant extracts: A comparison between synthesis processes and antihyperglycemic activity

EK Kambale, FM Katemo, J Quetin-Leclercq… - International journal of …, 2023 - Elsevier
Zinc oxide nanoparticles (ZnONPs) have shown antidiabetic activity in multiple studies and
can be produced by different plant-mediated (“green”) methods. This study aimed to …

Biological efficacy of zinc oxide nanoparticles against diabetes: a preliminary study conducted in mice

SA Siddiqui, MM Or Rashid, MG Uddin… - Bioscience …, 2020 - portlandpress.com
The antidiabetic, hypoglycemic and oral glucose tolerance test (OGTT) activities of zinc
oxide nanoparticles (ZnONPs) were assessed in mice. ZnONPs were prepared by reacting …

Zinc oxide nanoparticles induce an adverse effect on blood glucose levels depending on the dose and route of administration in healthy and diabetic rats

A Virgen-Ortiz, A Apolinar-Iribe, I Díaz-Reval… - Nanomaterials, 2020 - mdpi.com
Different studies in experimental diabetes models suggest that zinc oxide nanoparticles
(ZnONPs) are useful as antidiabetic agents. However, this evidence was performed and …

Evaluation of zinc-oxide nanoparticles effect on treatment of diabetes in streptozotocin-induced diabetic rats

M Afify, N Samy, NA Hafez… - Egyptian Journal of …, 2019 - ejchem.journals.ekb.eg
Aim: to produce unique products with novel properties, to manipulate materials at the nano-
scale level. Nanoparticles demonstrate novel or improved characteristics which are …

Green synthesis of zinc oxide nanoparticles using Croton joufra leaf extract, characterization and antidiabetic activity

AMA Ikbal, A Rajkhowa, WS Singh, K Manna - International Nano Letters, 2023 - Springer
In this current investigation, zinc oxide nanoparticles (ZnONPs) were synthesized from
Croton joufra leaves extract containing zinc nitrate as a precursor. Reducing zinc nitrate to …

The current and future perspectives of zinc oxide nanoparticles in the treatment of diabetes mellitus

K San Tang - Life sciences, 2019 - Elsevier
Diabetes mellitus (DM) is a multifaceted and costly disease, which requires serious
attention. Finding a cheaper anti-diabetic alternative that can act on multiple disease-related …

Zinc oxide nanoparticles show antidiabetic activity in streptozotocin-induced Type 1 and 2 diabetic rats

RD Umrani, KM Paknikar - Nanomedicine, 2014 - Taylor & Francis
Aim: The correlation of diabetes and an imbalance in zinc homeostasis makes zinc-based
therapy an attractive proposition. In this study, zinc oxide nanoparticles were evaluated for …

Protective role of biosynthesised zinc oxide nanoparticles on pancreatic beta cells: an in vitro and in vivo approach

AD John, A Ragavee, AD Selvaraj - IET nanobiotechnology, 2020 - Wiley Online Library
Sulphonylureas are extensively used in the treatment of type II diabetes; however, these
drugs have complications of hypoglycaemia and weight gain. The current study aims at …

[PDF][PDF] Therapeutic efficacy of zinc oxide nanoparticles in diabetic rats

MA Kamal, MH Khairy, NA ELSadek… - Slovenian Veterinary …, 2019 - academia.edu
This study attempted to scrutinize the potential efficacy of zinc oxide nanoparticles (ZnONPs)
and the standard oral hypoglycemic drug glibenclamide in streptozotocin (STZ) …