LBX2-AS1 as a novel diagnostic biomarker and therapeutic target facilitates multiple myeloma progression by enhancing mRNA stability of LBX2

H Jia, Y Liu, S Lv, R Qiao, X Zhang, F Niu… - Frontiers in Molecular …, 2021 - frontiersin.org
Objective: Multiple myeloma (MM) represents a common age-associated malignancy
globally. The function and underlying mechanism of antisense lncRNA LBX2-AS1 remain …

[HTML][HTML] SP1-upregulated LBX2-AS1 promotes the progression of glioma by targeting the miR-491-5p/LIF axis

W Li, I Soufiany, X Lyu, C Lu, Y Wei, Z Shi… - Journal of …, 2021 - ncbi.nlm.nih.gov
Background: Mounting evidences have shown the importance of lncRNAs in carcinogenesis
and cancer progression. LBX2-AS1 is identified as an oncogenic lncRNA that is abnormally …

RETRACTED ARTICLE: Long non-coding RNA LBX2-AS1 enhances glioma proliferation through downregulating microRNA-491-5p

Q Chen, J Gao, Y Zhao, R Hou - Cancer cell international, 2020 - Springer
Background Dysregulation of lncRNAs is frequent in glioma and has emerged as an
important mechanism involved in tumorigenesis. Previous analysis of Chinese Glioma …

Silencing of lncRNA LBX2-AS1 suppresses glioma cell proliferation and metastasis through the Akt/GSK3β pathway in vitro

H Wen, Z Li, S Song, L Xu, X Tong… - Acta biochimica et …, 2021 - academic.oup.com
Long non-coding RNAs (lncRNAs) have been proposed to play pivotal roles in the
tumorigenesis of various malignant tumors. Previous studies have found that lncRNA LBX2 …

Overexpression of long noncoding RNA LBX2-AS1 promotes the proliferation of colorectal cancer

Q Li, H Xie, Z Jin, J Huang, S Wang… - Technology in Cancer …, 2021 - journals.sagepub.com
Background: LBX2 antisense RNA 1 (LBX2-AS1), a long noncoding RNA, has been
identified to be closely associated with the progression of various cancers. However, the role …

LBX2‐AS1 promotes ovarian cancer progression by facilitating E2F2 gene expression via miR‐455‐5p and miR‐491‐5p sponging

J Cao, H Wang, G Liu, R Tang, Y Ding… - Journal of cellular …, 2021 - Wiley Online Library
LBX2‐AS1 is a long non‐coding RNA that facilitates the development of gastrointestinal
cancers and lung cancer, but its participation in ovarian cancer development remained …

LncRNA HOXB‐AS1 promotes cell growth in multiple myeloma via FUT4 mRNA stability by ELAVL1

R Chen, X Zhang, C Wang - Journal of cellular biochemistry, 2020 - Wiley Online Library
Multiple myeloma (MM) is defined as the second most common hematological tumor in the
globe. Long noncoding RNAs (lncRNAs) have been reported to play stimulative or …

ELK1‑mediated upregulation of lncRNA LBX2‑AS1 facilitates cell proliferation and invasion via regulating miR‑491‑5p/S100A11 axis in colorectal cancer

G Ma, W Dai, J Zhang, Q Li, B Gu… - International …, 2021 - spandidos-publications.com
The aim of the present study was to investigate the role and regulatory mechanism of LBX2
antisense RNA 1 (LBX2‑AS1) in colorectal cancer. Firstly, LBX2‑AS1 expression was …

[HTML][HTML] Focusing on long non-coding RNA dysregulation in newly diagnosed multiple myeloma

Y Shen, Y Feng, H Chen, L Huang, F Wang, J Bai… - Life sciences, 2018 - Elsevier
Aims Multiple myeloma (MM) is an incurable hematological cancer with a higher rate of
relapse. Alterations in the function of long non-coding RNAs (lncRNAs) promote the …

Retracted: Decreased expression of long noncoding RNA XLOC_013703 promotes cell growth via NF‐κB pathway in multiple myeloma

J Pu, H Huang, J Su, J Yuan, H Cong, X Wang… - IUBMB life, 2019 - Wiley Online Library
Long noncoding RNAs (lncRNAs) are dysregulated in cancer and involved in oncogenic or
tumor inhibitory processes. The aim of the study was to investigate the expression pattern of …