DNA methylation is a fundamental mechanism of epigenetic control in cells and its
dysregulation is strongly implicated in cancer development. Cancers possess an extensively …

Carcinogenesis is accompanied by widespread DNA methylation changes within the cell.
These changes are characterized by a globally hypomethylated genome with focal …

Cellular DNA undergoes profound changes in methylation during cancer development, with
hypermethylation occurring in specific gene promoters, amidst a backdrop of generalized …

Cancer is the second leading cause of death worldwide being responsible for 9.6 million
deaths in 2018. Epigenetic alterations are key in directing the aberrant expression of tumor …

Aberrant DNA methylation is ubiquitous in human cancer and has been shown to occur
early during carcinogenesis, thus providing attractive potential biomarkers for the early …

Tumor-acquired changes in DNA methylation are the focus of research in an increasing
number of basic, translational, and clinical laboratories around the world. In the laboratory …

DNA methylation is a stable covalent epigenetic modification of primarily CpG dinucleotides
that has recently gained considerable attention for its use as a biomarker in different clinical …

DNA methylation is an important and reversible epigenetic modification, which regulates
genomic stability and cellular plasticity. Faithful DNA methylation is essential for mammalian …

Lung, breast, colorectal, and prostate cancers are the most incident worldwide. Optimal
population-based cancer screening methods remain an unmet need, since cancer detection …

Simple Summary The detection of DNA methylation changes in blood has emerged as a
promising approach for cancer diagnosis and management. Our group has previously …