BRAFK601E Mutation in a Patient with a Follicular Thyroid Carcinoma

G Pennelli, F Vianello, S Barollo, R Pezzani… - Thyroid, 2011 - liebertpub.com
Background: BRAF mutations, the most common genetic alteration associated with papillary
thyroid carcinoma (PTC), have never been associated with follicular thyroid carcinoma (FTC) …

Characterization of a novel complex BRAF mutation in a follicular variant papillary thyroid carcinoma.

L Barzon, G Masi, IM Boschin, E Lavezzo… - European journal of …, 2008 - academic.oup.com
Introduction Activating mutations of the BRAF oncogene are frequently detected in papillary
thyroid carcinoma (PTC) and have been associated with a worse prognosis. The amino acid …

BRAFK601E Mutation in a Follicular Thyroid Adenoma: A Case Report

E Macerola, L Torregrossa, C Ugolini… - … journal of surgical …, 2017 - journals.sagepub.com
BRAF mutations represent the most common genetic alteration in papillary thyroid
carcinoma (PTC). The p. V600E mutation is specific for the classic and tall-cell variants of …

A Novel Complex BRAF Mutation Detected in a Solid Variant of Papillary Thyroid Carcinoma

S Chiosea, M Nikiforova, H Zuo, J Ogilvie, M Gandhi… - Endocrine …, 2009 - Springer
BRAF gene mutations are identified in about 45% of papillary thyroid carcinomas (PTC) and
represent the most common genetic event in this tumor. Here, we report a case of PTC, solid …

A new BRAF gene mutation detected in a case of a solid variant of papillary thyroid carcinoma

V Trovisco, P Soares, R Soares, J Magalhães… - Human pathology, 2005 - Elsevier
BRAF gene mutations have been frequently detected in papillary thyroid carcinoma (PTC).
Moreover, there is a close association between the type of mutation and the PTC histotype …

Correlation between BRAF mutation and the clinicopathological parameters in papillary thyroid carcinoma with particular reference to follicular variant

RA Smith, A Salajegheh, S Weinstein, M Nassiri… - Human pathology, 2011 - Elsevier
Mutation of the BRAF gene is common in thyroid cancer. Follicular variant of papillary thyroid
carcinoma is a variant of papillary thyroid carcinoma that has created continuous diagnostic …

Detection of BRAF mutation in thyroid papillary carcinomas by mutant allele-specific PCR amplification (MASA)

MR Sapio, D Posca, G Troncone… - European Journal of …, 2006 - academic.oup.com
Objective The somatic point mutation in the BRAF gene, which results in a valine-to-
glutamate substitution at residue 600 (BRAFV600E), is an ideal hallmark of papillary thyroid …

Mutational Patterns and Novel Mutations of the BRAF Gene in a Large Cohort of Korean Patients with Papillary Thyroid Carcinoma

CK Jung, SY Im, YJ Kang, H Lee, ES Jung, CS Kang… - Thyroid, 2012 - liebertpub.com
Background: BRAF mutation is the most common genetic event in papillary thyroid
carcinoma (PTC); however, the prevalence and patterns of the mutation vary worldwide. We …

[HTML][HTML] Expanding the Spectrum of BRAF Non-V600E Mutations in Thyroid Nodules: Evidence-Based Data from a Tertiary Referral Centre

A De Leo, D Serban, T Maloberti, V Sanza… - International Journal of …, 2023 - mdpi.com
The BRAF p. V600E mutation represents the most specific marker for papillary thyroid
carcinoma and is potentially related to aggressive behavior and persistent disease. BRAF …

BRAFV599E Mutation Is the Leading Genetic Event in Adult Sporadic Papillary Thyroid Carcinomas

E Puxeddu, S Moretti, R Elisei, C Romei… - The Journal of …, 2004 - academic.oup.com
Activating mutations of BRAF have been identified in a variety of human cancers, most
notably melanomas and papillary thyroid carcinomas (PTCs). The aim of the present study …