Clinical effectiveness of nirmatrelvir plus ritonavir in the treatment of COVID-19 in patients with cirrhosis

WH Hsu, BW Shiau, TH Liu, JY Wu… - Expert Review of Anti …, 2023 - Taylor & Francis
Objectives This retrospective cohort study assessed the clinical effectiveness of
nirmatrelvirplus ritonavir (NMV-r) in treating COVID-19 in patients with liver cirrhosis (LC) …

Liver tests abnormalities with licensed antiviral drugs for COVID-19: A narrative review

G Casalini, A Giacomelli, S Antinori - Expert Opinion on Drug Safety, 2022 - Taylor & Francis
Introduction Liver involvement in COVID-19 is multifactorial, and the three potential
mechanisms are direct hepatocyte viral damage, vascular or cellular damage during the …

[HTML][HTML] Challenges in COVID-19 drug treatment in patients with advanced liver diseases: A hepatology perspective

AS Hanafy, S Abd-Elsalam - World Journal of Gastroenterology, 2020 - ncbi.nlm.nih.gov
The global incidence of coronavirus disease 2019 (COVID-19) continues to increase despite
health care efforts. The disease is caused by coronavirus 2 with high transmission and …

Risk of acute liver injury following the nirmatrelvir/ritonavir use

CKH Wong, LY Mak, ICH Au, WY Cheng… - Liver …, 2023 - Wiley Online Library
Background Elevations in alanine aminotransferase (ALT) and aspartate aminotransferase
(AST) were reported as adverse events of nirmatrelvir/ritonavir users in the EPIC‐HR trial …

Clinical efficacy of nirmatrelvir plus ritonavir in patients with COVID-19 and preexisting cardiovascular diseases

TH Liu, JY Wu, PY Huang, WH Hsu… - Expert Review of Anti …, 2024 - Taylor & Francis
Background This study assessed the clinical efficacy of nirmatrelvir plus ritonavir (NMV-r) in
treating patients with COVID-19 who have preexisting cardiovascular diseases (CVDs) …

Minimal risk of drug-induced liver injury with Molnupiravir and Ritonavir-boosted Nirmatrelvir

GLH Wong, VWK Hui, TCF Yip, GCY Lui… - …, 2023 - gastrojournal.org
Molnupiravir and ritonavir-boosted nirmatrelvir are the 2 novel oral antiviral agents that have
recently been authorized for the treatment of mild to moderate COVID-19 in adults who are …

Comparison of Azvudine and Nirmatrelvir/Ritonavir and Combined Use in Patients with COVID-19

CY Hu, WS Cui, Y Lei, YW Tang, YY Zhang… - Infection and Drug …, 2023 - Taylor & Francis
Purpose To compare the effectiveness of azvudine and nirmatrelvir/ritonavir for the treatment
of coronavirus disease (COVID-19). Patients and Methods We conducted a retrospective …

[HTML][HTML] The effectiveness of oral anti-SARS-CoV-2 agents in non-hospitalized COVID-19 patients with nonalcoholic fatty liver disease: a retrospective study

CC Yang, YW Tsai, SH Wang, JY Wu, TH Liu… - Frontiers in …, 2024 - frontiersin.org
Background: The effectiveness of the novel oral antiviral agents, nirmatrelvir plus ritonavir
and molnupiravir, in treating COVID-19 in patients with nonalcoholic fatty liver disease is …

Efficacy of nirmatrelvir and ritonavir for post‐acute COVID‐19 sequelae beyond 3 months of SARS‐CoV‐2 infection

MH Chuang, JY Wu, TH Liu, WH Hsu… - Journal of Medical …, 2023 - Wiley Online Library
The effect of nirmatrelvir plus ritonavir (NMV‐r) on post‐acute COVID‐19 sequelae beyond 3
months of SARS‐CoV‐2 infection remains unknown. This retrospective cohort study utilized …

High rates of 30-day mortality in patients with cirrhosis and COVID-19

M Iavarone, R D'Ambrosio, A Soria, M Triolo… - Journal of …, 2020 - Elsevier
Background & Aims Coronavirus disease 2019 (COVID-19) poses a major health threat to
healthy individuals and those with comorbidities, but its impact on patients with cirrhosis is …