[HTML][HTML] Crystal structure of an archaeal CorB magnesium transporter
CNNM/CorB proteins are a broadly conserved family of integral membrane proteins with
close to 90,000 protein sequences known. They are associated with Mg2+ transport but it is …
close to 90,000 protein sequences known. They are associated with Mg2+ transport but it is …
A structural basis for Mg2+ homeostasis and the CorA translocation cycle
J Payandeh, EF Pai - The EMBO journal, 2006 - embopress.org
We describe the CorA Mg2+ transporter homologue from Thermotoga maritima in complex
with 12 divalent cations at 3.7 Å resolution. One metal is found near the universally …
with 12 divalent cations at 3.7 Å resolution. One metal is found near the universally …
Structural basis for the Mg2+ recognition and regulation of the CorC Mg2+ transporter
The CNNM/CorC family proteins are Mg2+ transporters that are widely distributed in all
domains of life. In bacteria, CorC has been implicated in the survival of pathogenic …
domains of life. In bacteria, CorC has been implicated in the survival of pathogenic …
Structural insights into the mechanisms of Mg2+ uptake, transport, and gating by CorA
A Guskov, N Nordin, A Reynaud… - Proceedings of the …, 2012 - National Acad Sciences
Despite the importance of Mg2+ for numerous cellular activities, the mechanisms underlying
its import and homeostasis are poorly understood. The CorA family is ubiquitous and is …
its import and homeostasis are poorly understood. The CorA family is ubiquitous and is …
[HTML][HTML] Structural and functional comparison of magnesium transporters throughout evolution
GAC Franken, MA Huynen, LA Martínez-Cruz… - Cellular and Molecular …, 2022 - Springer
Abstract Magnesium (Mg2+) is the most prevalent divalent intracellular cation. As co-factor in
many enzymatic reactions, Mg2+ is essential for protein synthesis, energy production, and …
many enzymatic reactions, Mg2+ is essential for protein synthesis, energy production, and …
Crystal structure of a divalent metal ion transporter CorA at 2.9 angstrom resolution
S Eshaghi, D Niegowski, A Kohl, DM Molina, SA Lesley… - Science, 2006 - science.org
CorA family members are ubiquitously distributed transporters of divalent metal cations and
are considered to be the primary Mg2+ transporter of Bacteria and Archaea. We have …
are considered to be the primary Mg2+ transporter of Bacteria and Archaea. We have …
Crystal structure of the CorA Mg2+ transporter
VV Lunin, E Dobrovetsky, G Khutoreskaya, R Zhang… - Nature, 2006 - nature.com
Abstract The magnesium ion, Mg2+, is essential for myriad biochemical processes and
remains the only major biological ion whose transport mechanisms remain unknown. The …
remains the only major biological ion whose transport mechanisms remain unknown. The …
[PDF][PDF] Mg2+-ATP sensing in CNNM, a putative magnesium transporter
The family of cystathionine-β-synthase (CBS)-pair domain divalent metal cation transport
mediators (CNNMs) is composed of four integral membrane proteins associated with Mg 2+ …
mediators (CNNMs) is composed of four integral membrane proteins associated with Mg 2+ …
The CorA magnesium transporter gene family
DG Kehres, CH LAWYER… - Microbial & comparative …, 1998 - liebertpub.com
The CorA transport system is the primary Mg2+ influx system of Salmonella typhimurium and
Escherichia coli. The CorA protein has no homology to any other known family of proteins. It …
Escherichia coli. The CorA protein has no homology to any other known family of proteins. It …
Structural asymmetry in the magnesium channel CorA points to sequential allosteric regulation
R Pfoh, A Li, N Chakrabarti… - Proceedings of the …, 2012 - National Acad Sciences
Magnesium ions (Mg2+) are essential for life, but the mechanisms regulating their transport
into and out of cells remain poorly understood. The CorA-Mrs2-Alr1 superfamily of Mg2+ …
into and out of cells remain poorly understood. The CorA-Mrs2-Alr1 superfamily of Mg2+ …