Maternal obesity is an important risk factor for obesity, cardiovascular, and metabolic
diseases in the offspring. Studies have shown that it leads to hypothalamic inflammation in …

Growing evidence supports a link between maternal nutrition and obesity in offspring.
Indeed, epidemiological data suggest that excess nutrition and growth during pre-and/or …

Maternal obesity is exceedingly common and strongly linked to offspring obesity and
metabolic disease. Hypothalamic function is critical to obesity development. Hypothalamic …

The arcuate nucleus (ARC) regulates body weight in response to blood-borne signals of
energy balance. Blood-brain barrier (BBB) permeability in the ARC is determined by …

As obesity rates have risen around the world, so to have pregnancies complicated by
maternal obesity. Obesity during pregnancy is not only associated with negative health …

Objective Perinatal exposure to maternal obesity results in predisposition of offspring to
develop obesity later in life. Increased weight gain in offspring exposed to maternal obesity …

Maternal obesity before or during pregnancy has been associated previously in offspring
with a wide range of poor neurodevelopmental outcomes and mental health problems. The …

Objective Maternal overnutrition is associated with adverse outcomes in offspring, including
increased risk for obesity and diabetes. Here, we aim to test the effects of maternal obesity …

A maternal high-fat diet affects offspring neurodevelopment with long-term consequences on
their brain health and behavior. During the past three decades, obesity has rapidly …

Purpose Maternal obesity has emerged as an important risk factor for the development of
metabolic disorders in the offspring. The hypothalamus as the center of energy homeostasis …