Dual Effects of 3-epi-betulin from Daphniphyllum glaucescens in Suppressing SARS-CoV-2-Induced Inflammation and Inhibiting Virus Entry

YJ Yeh, TL Chao, YJ Chang, SY Chang, CH Lu… - International Journal of …, 2023 - mdpi.com
The continuous emergence of SARS-CoV-2 variants has led to a protracted global COVID-
19 pandemic with significant impacts on public health and global economy. While there are …

High-content screening of Thai medicinal plants reveals Boesenbergia rotunda extract and its component Panduratin A as anti-SARS-CoV-2 agents

P Kanjanasirirat, A Suksatu, S Manopwisedjaroen… - Scientific reports, 2020 - nature.com
Since December 2019, the emergence of severe acute respiratory syndrome coronavirus-2
(SARS-CoV-2) has caused severe pneumonia, a disease named COVID-19, that became …

Plant-derived antiviral compounds as potential entry inhibitors against spike protein of SARS-CoV-2 wild-type and delta variant: an integrative in silicoapproach

JM Ambrose, M Kullappan, S Patil, KJ Alzahrani… - Molecules, 2022 - mdpi.com
The wild-type SARS-CoV-2 has continuously evolved into several variants with increased
transmissibility and virulence. The Delta variant which was initially identified in India created …

[HTML][HTML] A Natural Bioactive Peptide from Pinctada fucata Pearls Can Be Used as a Potential Inhibitor of the Interaction between SARS-CoV-2 and ACE2 against …

Y Wang, Q Wang, X Chen, B Li, Z Zhang, L Yao… - International Journal of …, 2024 - mdpi.com
The frequent occurrence of viral infections poses a serious threat to human life. Identifying
effective antiviral components is urgent. In China, pearls have been important traditional …

[PDF][PDF] Dose-dependent effect of berberine on SARS-CoV-2 spike protein induced inflammatory host cell response

I Gu, W Zhu - Int. J. Med. Sci. Health Res, 2021 - ijmshr.com
The novel Coronavirus disease 2019 (COVID-19) is the cause behind the current global
pandemic, capable of inducing pneumonia-like symptoms and lung failure. A key pathway …

Peimine inhibits variants of SARS‐CoV‐2 cell entry via blocking the interaction between viral spike protein and ACE2

WJ Wang, Y Chen, WC Su, YY Liu… - Journal of Food …, 2022 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19) is caused by the novel severe acute
respiratory syndrome coronavirus 2 (SARS‐CoV‐2). Several vaccines against SARS‐CoV‐2 …

The discovery of potential natural products for targeting SARS-CoV-2 spike protein by virtual screening

GY Chen, TY Yao, A Ahmed, YC Pan, JC Yang, YC Wu - bioRxiv, 2020 - biorxiv.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) enters into the cells
through its spike proteins binding to human angiotensin-converting enzyme 2 (ACE2) …

Phillyrin (KD-1) exerts anti-viral and anti-inflammatory activities against novel coronavirus (SARS-CoV-2) and human coronavirus 229E (HCoV-229E) by suppressing …

Q Ma, R Li, W Pan, W Huang, B Liu, Y Xie, Z Wang… - Phytomedicine, 2020 - Elsevier
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
extensively and rapidly spread in the world, causing an outbreak of acute infectious …

[PDF][PDF] A drug repurposing approach towards elucidating the potential of flavonoids as COVID-19 spike protein inhibitors

P Pandey, F Khan, AK Rana, Y Srivastava… - … Res. Appl. Chem, 2021 - researchgate.net
The novel coronavirus (nCoV) has emerged as a severe public health threat globally in the
21st century. Several therapies were reported towards identifying ligand against …

[HTML][HTML] Anemoside B4 inhibits SARS-CoV-2 replication in vitro and in vivo

M Xiao, R Luo, Q Liang, H Jiang, Y Liu, G Xu… - Chinese Herbal …, 2024 - Elsevier
Abstract Objective Anemoside B4 (AB4), the most abundant triterpenoidal saponin isolated
from Pulsatilla chinensis, inhibited influenza virus FM1 or Klebsiella pneumoniae-induced …