Demystifying mRNA vaccines: an emerging platform at the forefront of cryptic diseases

NZ Rouf, S Biswas, N Tarannum, LM Oishee… - RNA biology, 2022 - Taylor & Francis
Messenger RNA (mRNA) vaccines have been studied for decades, but only recently, during
the COVID-19 pandemic, has the technology garnered noteworthy attention. In contrast to …

Messenger RNA-based vaccines: Past, present, and future directions in the context of the COVID-19 pandemic

S Jain, A Venkataraman, ME Wechsler… - Advanced drug delivery …, 2021 - Elsevier
Abstract mRNA vaccines have received major attention in the fight against COVID-19.
Formulations from companies such as Moderna and BioNTech/Pfizer have allowed us to …

mRNA vaccines for COVID-19 and diverse diseases

A Hussain, H Yang, M Zhang, Q Liu, G Alotaibi… - Journal of Controlled …, 2022 - Elsevier
Since its outbreak in late 2019, the novel coronavirus disease 2019 (COVID-19) has spread
to every continent on the planet. The global pandemic has affected human health and …

[HTML][HTML] COVID-19 mRNA vaccines: Platforms and current developments

GT Szabó, AJ Mahiny, I Vlatkovic - Molecular Therapy, 2022 - cell.com
Since the first successful application of messenger ribonucleic acid (mRNA) as a vaccine
agent in a preclinical study nearly 30 years ago, numerous advances have been made in …

[HTML][HTML] mRNA vaccines: A novel weapon to control infectious diseases

Y Tian, Z Deng, P Yang - Frontiers in Microbiology, 2022 - frontiersin.org
Infectious diseases have always threatened human life, but with the development of
vaccines, effective strategies for preventing and controlling these diseases have become …

[HTML][HTML] Knife's edge: Balancing immunogenicity and reactogenicity in mRNA vaccines

J Lee, MC Woodruff, EH Kim, JH Nam - Experimental & Molecular …, 2023 - nature.com
Since the discovery of messenger RNA (mRNA), there have been tremendous efforts to
wield them in the development of therapeutics and vaccines. During the COVID-19 …

[HTML][HTML] mRNA vaccines in the COVID-19 pandemic and beyond

MJ Hogan, N Pardi - Annual review of medicine, 2022 - annualreviews.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of coronavirus
disease 2019 (COVID-19), emerged in China in December 2019 and quickly spread around …

[HTML][HTML] mRNA vaccines for COVID-19: what, why and how

JW Park, PNP Lagniton, Y Liu… - International journal of …, 2021 - ncbi.nlm.nih.gov
Abstract The Coronavirus disease-19 (COVID-19) pandemic, caused by severe acute
respiratory syndrome coronavirus-2 (SARS-CoV-2), has impacted human lives in the most …

[HTML][HTML] mRNA vaccines in disease prevention and treatment

G Zhang, T Tang, Y Chen, X Huang… - Signal transduction and …, 2023 - nature.com
Abstract mRNA vaccines have emerged as highly effective strategies in the prophylaxis and
treatment of diseases, thanks largely although not totally to their extraordinary performance …

[HTML][HTML] The importance of RNA-based vaccines in the fight against COVID-19: an overview

BAS Machado, KVS Hodel, LMS Fonseca… - Vaccines, 2021 - mdpi.com
In recent years, vaccine development using ribonucleic acid (RNA) has become the most
promising and studied approach to produce safe and effective new vaccines, not only for …