The endocannabinoid (eCB) system has emerged as a central integrator linking the
perception of external and internal stimuli to distinct neurophysiological and behavioural …

The endocannabinoid system is widely expressed in the limbic system, prefrontal cortical
areas, and brain structures regulating neuroendocrine stress responses, which explains the …

Evidence for the involvement of the endocannabinoid system (ECS) in anxiety and fear has
been accumulated, providing leads for novel therapeutic approaches. In anxiety, a …

Endogenous cannabinoids play an important role in the physiology and behavioral
expression of stress responses. Activation of the hypothalamic–pituitary–adrenal (HPA) axis …

The appropriate control of emotional responses evoked by environmental stimuli is an
important innate mechanism for ensuring quality of life and even for survival. Inappropriate …

Two topics are presented in this review. In the first section, we review data regarding the
effects of the endocannabinoids (eCBs) and cannabinoid receptors on neuroimmune …

The endocannabinoid signaling system (ECSS) is altered by exposure to stress and
mediates and modulates the effects of stress on the brain. Considerable preclinical data …

Accumulating evidence over the past decade has highlighted an important role of the
endocannabinoid (eCB) system in the regulation of stress and emotional behavior across …

The stress response is associated with a broad spectrum of physiological and behavioural
effects including hypothalamo-pituitary-adrenal (HPA) axis activation, altered central …

The endocannabinoid system recently emerged as an important modulator of many
neuronal functions. Among them, the control of anxiety and acquired fear represents …