Data-efficient and weakly supervised computational pathology on whole-slide images

MY Lu, DFK Williamson, TY Chen, RJ Chen… - Nature biomedical …, 2021 - nature.com
Deep-learning methods for computational pathology require either manual annotation of
gigapixel whole-slide images (WSIs) or large datasets of WSIs with slide-level labels and …

Clinical-grade computational pathology using weakly supervised deep learning on whole slide images

G Campanella, MG Hanna, L Geneslaw, A Miraflor… - Nature medicine, 2019 - nature.com
The development of decision support systems for pathology and their deployment in clinical
practice have been hindered by the need for large manually annotated datasets. To …

An annotation-free whole-slide training approach to pathological classification of lung cancer types using deep learning

CL Chen, CC Chen, WH Yu, SH Chen… - Nature …, 2021 - nature.com
Deep learning for digital pathology is hindered by the extremely high spatial resolution of
whole-slide images (WSIs). Most studies have employed patch-based methods, which often …

Benchmarking weakly-supervised deep learning pipelines for whole slide classification in computational pathology

NG Laleh, HS Muti, CML Loeffler, A Echle… - Medical image …, 2022 - Elsevier
Artificial intelligence (AI) can extract visual information from histopathological slides and
yield biological insight and clinical biomarkers. Whole slide images are cut into thousands of …

Differentiable zooming for multiple instance learning on whole-slide images

K Thandiackal, B Chen, P Pati, G Jaume… - … on Computer Vision, 2022 - Springer
Abstract Multiple Instance Learning (MIL) methods have become increasingly popular for
classifying gigapixel-sized Whole-Slide Images (WSIs) in digital pathology. Most MIL …

Morphological prototyping for unsupervised slide representation learning in computational pathology

AH Song, RJ Chen, T Ding… - Proceedings of the …, 2024 - openaccess.thecvf.com
Abstract Representation learning of pathology whole-slide images (WSIs) has been has
primarily relied on weak supervision with Multiple Instance Learning (MIL). However the …

A multi-resolution model for histopathology image classification and localization with multiple instance learning

J Li, W Li, A Sisk, H Ye, WD Wallace, W Speier… - Computers in biology …, 2021 - Elsevier
Large numbers of histopathological images have been digitized into high resolution whole
slide images, opening opportunities in developing computational image analysis tools to …

Weakly supervised joint whole-slide segmentation and classification in prostate cancer

P Pati, G Jaume, Z Ayadi, K Thandiackal… - Medical Image …, 2023 - Elsevier
The identification and segmentation of histological regions of interest can provide significant
support to pathologists in their diagnostic tasks. However, segmentation methods are …

Multiple instance learning with center embeddings for histopathology classification

P Chikontwe, M Kim, SJ Nam, H Go… - Medical Image Computing …, 2020 - Springer
Histopathology image analysis plays an important role in the treatment and diagnosis of
cancer. However, analysis of whole slide images (WSI) with deep learning is challenging …

Semi-supervised histology classification using deep multiple instance learning and contrastive predictive coding

MY Lu, RJ Chen, J Wang, D Dillon… - arXiv preprint arXiv …, 2019 - arxiv.org
Convolutional neural networks can be trained to perform histology slide classification using
weak annotations with multiple instance learning (MIL). However, given the paucity of …