Infrared spectral histopathology (SHP): a novel diagnostic tool for the accurate classification of lung cancer

B Bird, M Miljković, S Remiszewski, A Akalin… - Laboratory …, 2012 - nature.com
We report results of a study utilizing a recently developed tissue diagnostic method, based
on label-free spectral techniques, for the classification of lung cancer histopathological …

[HTML][HTML] Classification of malignant and benign tumors of the lung by infrared spectral histopathology (SHP)

A Akalin, X Mu, MA Kon, A Ergin, SH Remiszewski… - Laboratory …, 2015 - Elsevier
We report results of a study utilizing a novel tissue classification method, based on label-free
spectral techniques, for the classification of lung cancer histopathological samples on a …

The infrared spectral signatures of disease: extracting the distinguishing spectral features between normal and diseased states

M Diem, K Papamarkakis, J Schubert… - Applied …, 2009 - journals.sagepub.com
Over the past decade, new med-ical diagnostic methods have been developed by several
research groups worldwide, based on infrared microspectroscopy and microscopic imaging …

Immunohistochemistry, histopathology and infrared spectral histopathology of colon cancer tissue sections

A Kallenbach‐Thieltges… - Journal of …, 2013 - Wiley Online Library
During the past years, many studies have shown that infrared spectral histopathology (SHP)
can distinguish different tissue types and disease types independently of morphological …

Hyperspectral microscopic analysis of normal, benign and carcinoma microarray tissue sections

M Maggioni, GL Davis, FJ Warner… - Optical Biopsy …, 2006 - spiedigitallibrary.org
We apply a unique micro-optoelectromechanical tuned light source and new algorithms to
the hyper-spectral microscopic analysis of human colon biopsies. The tuned light prototype …

Distinguishing cell types or populations based on the computational analysis of their infrared spectra

FL Martin, JG Kelly, V Llabjani, PL Martin-Hirsch… - Nature protocols, 2010 - nature.com
Infrared (IR) spectroscopy of intact cells results in a fingerprint of their biochemistry in the
form of an IR spectrum; this has given rise to the new field of biospectroscopy. This protocol …

Multivariate classification of the infrared spectra of cell and tissue samples

DM Haaland, HDT Jones… - Applied spectroscopy, 1997 - journals.sagepub.com
Infrared microspectroscopy of biopsied canine lymph cells and tissue was performed to
investigate the possibility of using IR spectra coupled with multivariate classification …

Infrared micro-spectral imaging: distinction of tissue types in axillary lymph node histology

B Bird, M Miljkovic, MJ Romeo, J Smith, N Stone… - BMC clinical …, 2008 - Springer
Background Histopathologic evaluation of surgical specimens is a well established
technique for disease identification, and has remained relatively unchanged since its clinical …

Identifying variables responsible for clustering in discriminant analysis of data from infrared microspectroscopy of a biological sample

FL Martin, MJ German, E Wit, T Fearn… - Journal of …, 2007 - liebertpub.com
In the biomedical field, infrared (IR) spectroscopic studies can involve the processing of data
derived from many samples, divided into classes such as category of tissue (eg, normal or …

Molecular profiling of individual tumor cells by hyperspectral microscopic imaging

JW Uhr, ML Huebschman, EP Frenkel, NL Lane… - Translational …, 2012 - Elsevier
We developed a hyperspectral microscopic imaging (HMI) platform that can precisely
identify and quantify 10 molecular markers in individual cancer cells in a single pass. The …