Bitter taste perception plays vital roles in animal behavior and fitness. By signaling the
presence of toxins in foods, particularly noxious defense compounds found in plants, it …

Vertebrate Tas2r taste receptors bind to bitter compounds, which are typically poisonous, to
elicit bitter sensation to prevent the ingestion of toxins. Previous studies noted a marked …

Bitter taste receptors (TAS2Rs) enable animals to detect and avoid toxins in the
environment, including noxious defense compounds produced by plants. This suggests that …

Bitter is the most complex of human tastes, and is arguably the most important. Aversion to
bitter taste is important for detecting toxic compounds in food; however, many beneficial …

The recognition of potentially harmful food components by the gustatory system is important
for survival and well-being of vertebrates. The plethora of structurally diverse bitter …

A family of approximately 30 TAS2R bitter taste receptors has been identified in mammals.
Their genes evolved through adaptive diversification and are linked to chromosomal loci …

Bitter taste perception in vertebrates relies on a variable number of bitter taste receptor
(Tas2r) genes, ranging from only three functional genes in chicken to as many as …

One key to animal survival is the detection and avoidance of potentially harmful compounds
by their bitter taste. Variable numbers of taste 2 receptor genes expressed in the gustatory …

The molecular basis of human bitter taste perception is an area of intense research. Only 25
G protein‐coupled receptors belonging to the hTAS2R gene family face the challenge to …

Bitter taste prevents mammals from ingesting food potentially contaminated with bitter‐
tasting toxins, which are frequent and structurally diverse. It is mediated by a family of …