High-depth African genomes inform human migration and health

A Choudhury, S Aron, LR Botigué, D Sengupta… - Nature, 2020 - nature.com
The African continent is regarded as the cradle of modern humans and African genomes
contain more genetic variation than those from any other continent, yet only a fraction of the …

[HTML][HTML] The African genome variation project shapes medical genetics in Africa

D Gurdasani, T Carstensen, F Tekola-Ayele, L Pagani… - Nature, 2015 - nature.com
Given the importance of Africa to studies of human origins and disease susceptibility,
detailed characterization of African genetic diversity is needed. The African Genome …

The genomic landscape of African populations in health and disease

CN Rotimi, AR Bentley, AP Doumatey… - Human molecular …, 2017 - academic.oup.com
A deeper appreciation of the complex architecture of African genomes is critical to the global
effort to understand human history, biology and differential distribution of disease by …

[HTML][HTML] A continuum of admixture in the Western Hemisphere revealed by the African Diaspora genome

RA Mathias, MA Taub, CR Gignoux, W Fu… - Nature …, 2016 - nature.com
Abstract The African Diaspora in the Western Hemisphere represents one of the largest
forced migrations in history and had a profound impact on genetic diversity in modern …

[HTML][HTML] Whole-genome sequencing for an enhanced understanding of genetic variation among South Africans

A Choudhury, M Ramsay, S Hazelhurst, S Aron… - Nature …, 2017 - nature.com
Abstract The Southern African Human Genome Programme is a national initiative that
aspires to unlock the unique genetic character of southern African populations for a better …

[HTML][HTML] Evaluating the promise of inclusion of African ancestry populations in genomics

AR Bentley, SL Callier, CN Rotimi - NPJ genomic medicine, 2020 - nature.com
The lack of representation of diverse ancestral backgrounds in genomic research is well-
known, and the resultant scientific and ethical limitations are becoming increasingly …

[PDF][PDF] Uganda genome resource enables insights into population history and genomic discovery in Africa

D Gurdasani, T Carstensen, S Fatumo, G Chen… - Cell, 2019 - cell.com
Genomic studies in African populations provide unique opportunities to understand disease
etiology, human diversity, and population history. In the largest study of its kind, comprising …

Sequence three million genomes across Africa

A Wonkam - Nature, 2021 - nature.com
Sequence three million genomes across Africa Skip to main content Thank you for visiting
nature.com. You are using a browser version with limited support for CSS. To obtain the best …

[HTML][HTML] Genomic ancestry of North Africans supports back-to-Africa migrations

BM Henn, LR Botigué, S Gravel, W Wang… - PLoS …, 2012 - journals.plos.org
North African populations are distinct from sub-Saharan Africans based on cultural,
linguistic, and phenotypic attributes; however, the time and the extent of genetic divergence …

Extensive admixture and selective pressure across the Sahel Belt

P Triska, P Soares, E Patin, V Fernandes… - Genome biology and …, 2015 - academic.oup.com
Genome-wide studies of African populations have the potential to reveal powerful insights
into the evolution of our species, as these diverse populations have been exposed to …