Introduction: The available therapeutic strategies for Parkinson's disease (PD) rely only on the amelioration of the symptomatology of the disease, lacking neuroprotection or …
B Mendes-Pinheiro, SI Anjo, B Manadas… - … in bioengineering and …, 2019 - frontiersin.org
Parkinson's disease (PD) is characterized by a selective loss of dopamine (DA) neurons in the human midbrain causing motor dysfunctions. The exact mechanism behind …
Parkinson's disease is the second most prevalent neurodegenerative disorder worldwide. Clinically, it is characterized by severe motor complications caused by progressive …
The low regeneration potential of the central nervous system (CNS) represents a challenge for the development of new therapeutic strategies. Mesenchymal stem cells (MSCs) have …
Research in the last decade strongly suggests that mesenchymal stem cell (MSC)-mediated therapeutic benefits are mainly due to their secretome, which has been proposed as a …
Mesenchymal stem cells (MSCs) secretome: a good candidate for medical biotechnology? Medical biotechnology is currently defined as the application of biotechnological tools for …
M Ghasemi, E Roshandel, M Mohammadian… - Stem cell research & …, 2023 - Springer
Background Over the past few years, mesenchymal stromal cells (MSCs) have attracted a great deal of scientific attention owing to their promising results in the treatment of incurable …
B Mendes-Pinheiro, FG Teixeira, SI Anjo… - Stem cells …, 2018 - academic.oup.com
Parkinson's disease (PD) is a progressive neurodegenerative movement disorder that results from the death of dopamine (DA) neurons. Over recent years, differentiated or …
Transplantation of stem cells, in particular mesenchymal stem cells (MSCs), stands as a promising therapy for trauma, stroke or neurodegenerative conditions such as spinal cord or …