Combination anti-retroviral therapy (ART) has revolutionized the treatment and prevention of
HIV-1 infection. Taken daily, ART prevents and suppresses the infection. However, ART …

Combination antiretroviral therapy (ART) is highly effective in controlling human
immunodeficiency virus (HIV)-1 but requires lifelong medication due to the existence of a …

HIV-1 infection remains a public health problem with no cure. Anti-retroviral therapy (ART) is
effective but requires lifelong drug administration owing to a stable reservoir of latent …

Antiretroviral therapy is highly effective in suppressing human immunodeficiency virus (HIV).
However, eradication of the virus in individuals with HIV has not been possible to date …

Monotherapy of HIV-1 infection with single antiretroviral agents is ineffective because error-
prone HIV-1 replication leads to the production of drug-resistant viral variants …

Novel broadly neutralizing antibodies targeting HIV-1 hold promise for their use in the
prevention and treatment of HIV-1 infection. Pre-clinical results have encouraged the …

Combination antiretroviral therapy (cART) is effective but not curative, and no successful
vaccine is currently available for human immunodeficiency virus-1 (HIV-1). Broadly …

The bar is high to improve on current combination antiretroviral therapy (ART), now highly
effective, safe, and simple. However, antibodies that bind the HIV envelope are able to …

Human antibodies to human immunodeficiency virus-1 (HIV-1) can neutralize a broad range
of viral isolates in vitro and protect non-human primates against infection,. Previous work …

HIV-1 therapy with single or dual broadly neutralizing antibodies (bNAbs) has shown viral
escape, indicating that at least a triple bNAb therapy may be needed for robust suppression …