[HTML][HTML] Invited review: Good practices in genome-wide association studies to identify candidate sequence variants in dairy cattle

G Sahana, Z Cai, MP Sanchez, AC Bouwman… - Journal of Dairy …, 2023 - Elsevier
Genotype data from dairy cattle selection programs have greatly facilitated GWAS to identify
variants related to economic traits. Results can enhance the accuracy of genomic prediction …

[HTML][HTML] Weighting sequence variants based on their annotation increases the power of genome-wide association studies in dairy cattle

Z Cai, B Guldbrandtsen, MS Lund… - Genetics Selection …, 2019 - Springer
Background Genome-wide association studies (GWAS) are widely used to identify regions
of the genome that harbor genetic determinants of quantitative traits. However, the multiple …

[HTML][HTML] A validated genome-wide association study in 2 dairy cattle breeds for milk production and fertility traits using variable length haplotypes

JE Pryce, S Bolormaa, AJ Chamberlain… - Journal of dairy …, 2010 - Elsevier
Genome-wide association studies (GWAS) were used to discover genomic regions
explaining variation in dairy production and fertility traits. Associations were detected with …

[HTML][HTML] Multibreed genome wide association can improve precision of mapping causative variants underlying milk production in dairy cattle

LA Raven, BG Cocks, BJ Hayes - BMC genomics, 2014 - Springer
Background Genome wide association studies (GWAS) in most cattle breeds result in large
genomic intervals of significant associations making it difficult to identify causal mutations …

[HTML][HTML] Dissecting closely linked association signals in combination with the mammalian phenotype database can identify candidate genes in dairy cattle

Z Cai, B Guldbrandtsen, MS Lund, G Sahana - BMC genetics, 2019 - Springer
Background Genome-wide association studies (GWAS) have been successfully
implemented in cattle research and breeding. However, moving from the associations to …

[HTML][HTML] Confirmed effects of candidate variants for milk production, udder health, and udder morphology in dairy cattle

T Tribout, P Croiseau, R Lefebvre, A Barbat… - Genetics Selection …, 2020 - Springer
Background Over the last years, genome-wide association studies (GWAS) based on
imputed whole-genome sequences (WGS) have been used to detect quantitative trait loci …

[HTML][HTML] Sequence variants selected from a multi-breed GWAS can improve the reliability of genomic predictions in dairy cattle

I Van den Berg, D Boichard, MS Lund - Genetics Selection Evolution, 2016 - Springer
Background Sequence data can potentially increase the reliability of genomic predictions,
because such data include causative mutations instead of relying on linkage disequilibrium …

[HTML][HTML] Comparing power and precision of within-breed and multibreed genome-wide association studies of production traits using whole-genome sequence data for …

I van den Berg, D Boichard, MS Lund - Journal of Dairy Science, 2016 - Elsevier
The objective of this study was to compare mapping precision and power of within-breed
and multibreed genome-wide association studies (GWAS) and to compare the results …

[HTML][HTML] Regulatory and coding genome regions are enriched for trait associated variants in dairy and beef cattle

L Koufariotis, YPP Chen, S Bolormaa, BJ Hayes - BMC genomics, 2014 - Springer
Background In livestock, as in humans, the number of genetic variants that can be tested for
association with complex quantitative traits, or used in genomic predictions, is increasing …

[HTML][HTML] Multivariate analysis of a genome-wide association study in dairy cattle

S Bolormaa, JE Pryce, BJ Hayes, ME Goddard - Journal of dairy science, 2010 - Elsevier
Multiple-trait genome-wide association study (GWAS) analyses were compared with single-
trait GWAS for power to discover and subsequently validate genetic markers (single …