Side population (SP) cells are involved in the development of multidrug resistance (MDR) in
human multiple myeloma (MM), due to their cancer stem cell (CSC)‑like phenotypes. ATP …

The current researches have reported that circular RNA is an important regulatory factor in
the progression of various human disease. However, the function and mechanism of most …

The transmembrane transporter P-glycoprotein (P-gp) encoded by ABCB1, is one major
cause for multidrug resistance (MDR). We compared the genomic profile and gene …

The ATP-binding cassette, subfamily G, isoform 2 protein (ABCG2) is an important member
of the ABC transporter superfamily, which has been suggested to be involved in multidrug …

Efficacy of cancer chemotherapy may be impaired by tumor resistance to multiple,
structurally unrelated therapeutic drugs with different mechanisms of action, a phenomenon …

Multi-drug chemoresistance remains one of the most common reasons for chemotherapy
failure. The membrane transporter protein ABCG2/BCRP1 has been shown in vitro to …

Multidrug resistance (MDR) seriously limits the efficacy of chemotherapy in patients with
cancer and leukemia. Active transport across membranes is essential for such cellular drug …

Multidrug resistance remains a major obstacle to effective chemotherapy of colon cancer.
ABCG2, as a half-transporter of the G subfamily of ATP-binding cassette transporter genes …

Human ABCG2 is a member of the ATP-binding cassette (ABC) transporter superfamily and
is known to contribute to multidrug resistance (MDR) in cancer chemotherapy. Among ABC …

The frequent occurrence of multidrug resistance (MDR) conferred by the overexpression of
ATP-binding cassette (ABC) transporters ABCB1 and ABCG2 in cancer cells remains a …