Dendritic cells and cancer: from biology to therapeutic intervention

B Wylie, C Macri, JD Mintern, J Waithman - Cancers, 2019 - mdpi.com
Inducing effective anti-tumor immunity has become a major therapeutic strategy against
cancer. Dendritic cells (DC) are a heterogenous population of antigen presenting cells that …

Dendritic cells in cancer immunology and immunotherapy

SK Wculek, FJ Cueto, AM Mujal, I Melero… - Nature Reviews …, 2020 - nature.com
Dendritic cells (DCs) are a diverse group of specialized antigen-presenting cells with key
roles in the initiation and regulation of innate and adaptive immune responses. As such …

[HTML][HTML] The role of dendritic cells in tumor microenvironments and their uses as therapeutic targets

CW Kim, KD Kim, HK Lee - BMB reports, 2021 - ncbi.nlm.nih.gov
Dendritic cells (DC), which consist of several different subsets, specialize in antigen
presentation and are critical for mediating the innate and adaptive immune responses. DC …

Dendritic cells as orchestrators of anticancer immunity and immunotherapy

I Heras-Murillo, I Adán-Barrientos, M Galán… - Nature Reviews …, 2024 - nature.com
Dendritic cells (DCs) are a heterogeneous group of antigen-presenting innate immune cells
that regulate adaptive immunity, including against cancer. Therefore, understanding the …

Tumor-infiltrating dendritic cells in cancer pathogenesis

JM Tran Janco, P Lamichhane… - The Journal of …, 2015 - journals.aai.org
Dendritic cells (DCs) play a pivotal role in the tumor microenvironment, which is known to
affect disease progression in many human malignancies. Infiltration by mature, active DCs …

[HTML][HTML] Dendritic cells in the cancer microenvironment

Y Ma, GV Shurin, Z Peiyuan, MR Shurin - Journal of Cancer, 2013 - ncbi.nlm.nih.gov
The complexity of the tumor immunoenvironment is underscored by the emergence and
discovery of different subsets of immune effectors and regulatory cells. Tumor-induced …

Dendritic cells and cancer immunity

A Gardner, B Ruffell - Trends in immunology, 2016 - cell.com
Dendritic cells (DCs) are central regulators of the adaptive immune response, and as such
are necessary for T-cell-mediated cancer immunity. In particular, antitumoral responses …

Impaired function of dendritic cells within the tumor microenvironment

Z Xiao, R Wang, X Wang, H Yang, J Dong… - Frontiers in …, 2023 - frontiersin.org
Dendritic cells (DCs), a class of professional antigen-presenting cells, are considered key
factors in the initiation and maintenance of anti-tumor immunity due to their powerful ability …

Tumor-altered dendritic cell function: implications for anti-tumor immunity

KM Hargadon - Frontiers in immunology, 2013 - frontiersin.org
Dendritic cells (DC) are key regulators of both innate and adaptive immunity, and the array
of immunoregulatory functions exhibited by these cells is dictated by their differentiation …

The role of dendritic cells in cancer and anti-tumor immunity

AE Marciscano, N Anandasabapathy - Seminars in immunology, 2021 - Elsevier
Dendritic cells (DC) are key sentinels of the host immune response with an important role in
linking innate and adaptive immunity and maintaining tolerance. There is increasing …