New insights toward molecular and nanotechnological approaches to antidiabetic agents for Alzheimer's disease

SP Pradhan, PK Sahu, A Behera - Molecular and Cellular Biochemistry, 2023 - Springer
Alzheimer's disease (AD) is a chronic neurodegenerative disorder affecting a major class of
silver citizens. The disorder shares a mutual relationship on account of its cellular and …

A nanotechnological approach to the management of Alzheimer disease and type 2 diabetes

Q Alam, M ZubairAlam, S Karim… - CNS & Neurological …, 2014 - ingentaconnect.com
Alzheimer's disease (AD) and type 2 diabetes (T2D) are both prevalent in older individuals
and have gained significant attention due to alarming rates of increase. The high incidences …

Mechanistic and Etiological Similarities in Diabetes Mellitus and Alzheimer's Disease: Antidiabetic Drugs as Optimistic Therapeutics in Alzheimer's Disease

S Das, AK Ramachandran, D Halder… - CNS & Neurological …, 2023 - ingentaconnect.com
Background: Diabetes mellitus and Alzheimer's disease are two common diseases that
majorly affect the elderly population. Patients in both cases are increasing day by day. They …

Diabetic theory in anti-Alzheimer's drug research and development-Part 1: therapeutic potential of antidiabetic agents

A Jankowska, A Wesołowska… - Current Medicinal …, 2020 - ingentaconnect.com
Alzheimer's Disease (AD) is a chronic and progressive neurodegenerative disorder that
affects over 46 million people worldwide. It is characterized by a decline in cognitive …

Molecular and biochemical pathways encompassing diabetes mellitus and dementia

T Behl, A Arora, A Sehgal, S Singh… - CNS & Neurological …, 2022 - ingentaconnect.com
Diabetes mellitus is a major metabolic disorder that has now emerged as an epidemic, and it
affects the brain through an array of pathways. Patients with diabetes mellitus can develop …

Assessing the Clinical Correlation between Alzheimer's disease and Type-2 Diabetes Mellitus: Current Strategies and Emerging Perspectives

J Parekh, H Shende, A Kumar, HS Tuli… - Current Pharmacology …, 2024 - Springer
Abstract Purpose of Review This article aims to provide a brief overview of novel therapeutic
approaches for combating type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD) …

Unwinding complexities of diabetic Alzheimer by potent novel molecules

S Gupta, A Nair, V Jhawat, N Mustaq… - American Journal of …, 2020 - journals.sagepub.com
Diabetes mellitus is one of the aggressive disorders in global society. No pharmacotherapy
is available for permanent diabetes cure, although management is possible with drugs and …

Repositioning of anti-diabetic drugs against dementia: insight from molecular perspectives to clinical trials

KEK Mantik, S Kim, B Gu, S Moon, HB Kwak… - International journal of …, 2023 - mdpi.com
Insulin resistance as a hallmark of type 2 DM (T2DM) plays a role in dementia by promoting
pathological lesions or enhancing the vulnerability of the brain. Numerous studies related to …

[HTML][HTML] Alzheimer's disease and type 2 diabetes mellitus: Pathophysiologic and pharmacotherapeutics links

M Rojas, M Chávez-Castillo, J Bautista… - World Journal of …, 2021 - ncbi.nlm.nih.gov
At present, Alzheimer's disease (AD) and type 2 diabetes mellitus (T2DM) are two highly
prevalent disorders worldwide, especially among elderly individuals. T2DM appears to be …

Bridging type 2 diabetes and Alzheimer's disease: assembling the puzzle pieces in the quest for the molecules with therapeutic and preventive potential

AM de Matos, MP de Macedo… - Medicinal Research …, 2018 - Wiley Online Library
Abstract Type 2 diabetes (T2D) and Alzheimer's disease (AD) are two age‐related amyloid
diseases that affect millions of people worldwide. Broadly supported by epidemiological …