Heart disease is a significant health concern for elderly individuals, with heart aging being
the primary cause. Recent studies have shown that autophagy can play a protective role in …

Background Myocardial fibrosis is a common pathological manifestation of many
cardiovascular diseases at the end stage. Autophagy has been demonstrated to play a …

To investigate the effects of saponins extracted from Panax japonicus (SPJ) on
cardiomyocyte apoptosis in natural aging rats and explore its underlying mechanisms. SD …

Panax notoginseng saponins (PNS) have been widely used in the cardiovascular system for
the treatment of cardiovascular diseases and stroke in China. In this study, we investigated …

Sleep deprivation (SD) may lead to serious myocardial injury in cardiovascular diseases.
Saponins extracted from the roots of Panax notoginseng, a traditional Chinese medicine …

Advanced glycation end products (AGEs) have been identified to transduce fibrogenic
signals via inducing the activation of their receptor (RAGE)‐mediated pathway. Recently …

Context Panax japonicus is the dried rhizome of Panax japonicus CA Mey.(Araliaceae).
Saponins from Panax japonicus (SPJ) exhibit anti-oxidative and anti-aging effects. Objective …

Background: Oxidative stress and mitochondrial dysfunction play a vital role in the
pathogenesis of brain aging. Saponins from Panax japonicus (SPJ) have attracted much …

Context Panax japonicus is the dried rhizome of Panax japonicus CA Mey.(Araliaceae).
Saponins from Panax japonicus (SPJ) exhibit anti-inflammatory and antioxidative effects …

The present study examined whether Panax notoginseng saponins (PNS) alleviated
advanced glycation end product (AGE)‑induced apoptosis in human umbilical vein …