Intestinal cell damage and systemic immune activation in individuals reporting sensitivity to wheat in the absence of coeliac disease

M Uhde, M Ajamian, G Caio, R De Giorgio, A Indart… - Gut, 2016 - gut.bmj.com
Objective Wheat gluten and related proteins can trigger an autoimmune enteropathy, known
as coeliac disease, in people with genetic susceptibility. However, some individuals …

Non-celiac gluten sensitivity: questions still to be answered despite increasing awareness

U Volta, G Caio, F Tovoli, R De Giorgio - Cellular & molecular …, 2013 - nature.com
Recently, the increasing number of patients worldwide who are sensitive to dietary gluten
without evidence of celiac disease or wheat allergy has contributed to the identification of a …

Duodenal and rectal mucosa inflammation in patients with non-celiac wheat sensitivity

A Carroccio, G Giannone, P Mansueto, M Soresi… - Clinical …, 2019 - Elsevier
Background & Aims Studies of non-celiac gluten or wheat sensitivity (NCGWS) have
increased but there are no biomarkers of this disorder. We aimed to evaluate histologic …

High proportions of people with nonceliac wheat sensitivity have autoimmune disease or antinuclear antibodies

A Carroccio, A D'Alcamo, F Cavataio, M Soresi… - Gastroenterology, 2015 - Elsevier
Background & Aims There is much interest in wheat sensitivity among people without celiac
disease (CD), but little is known about any risks associated with the condition. We evaluated …

Elevated serum interleukin‐2 after gluten correlates with symptoms and is a potential diagnostic biomarker for coeliac disease

JA Tye‐Din, AJM Daveson, HC Ee… - Alimentary …, 2019 - Wiley Online Library
Background Coeliac disease patients on a gluten‐free diet experience reactions to gluten,
but these are not well characterised or understood. Systemic cytokine release was recently …

[HTML][HTML] Celiac disease and autoimmunity: review and controversies

JM Denham, ID Hill - Current allergy and asthma reports, 2013 - Springer
Celiac disease (CD) is an autoimmune condition affecting the small intestine, triggered by
the ingestion of gluten, the protein fraction of wheat, barley, and rye. There is a strong …

Gliadin does not induce mucosal inflammation or basophil activation in patients with nonceliac gluten sensitivity

C Bucci, F Zingone, I Russo, I Morra, R Tortora… - Clinical …, 2013 - Elsevier
Background & Aims Nonceliac gluten-sensitive (NCGS) patients report intestinal and extra-
intestinal symptoms shortly after ingesting gluten; these symptoms disappear on gluten-free …

[HTML][HTML] Divergence of gut permeability and mucosal immune gene expression in two gluten-associated conditions: celiac disease and gluten sensitivity

A Sapone, KM Lammers, V Casolaro, M Cammarota… - BMC medicine, 2011 - Springer
Background Celiac disease (CD) is an autoimmune enteropathy triggered by the ingestion
of gluten. Gluten-sensitive individuals (GS) cannot tolerate gluten and may develop …

Celiac disease and nonceliac gluten sensitivity: a review

MM Leonard, A Sapone, C Catassi, A Fasano - Jama, 2017 - jamanetwork.com
Importance The prevalence of gluten-related disorders is rising, and increasing numbers of
individuals are empirically trying a gluten-free diet for a variety of signs and symptoms. This …

Non-celiac gluten sensitivity: a work-in-progress entity in the spectrum of wheat-related disorders

U Volta, G Caio, R De Giorgio, C Henriksen… - Best Practice & …, 2015 - Elsevier
Non-celiac gluten sensitivity is an undefined syndrome with gastrointestinal and extra-
intestinal manifestations triggered by gluten in patients without celiac disease and wheat …