Effect of probiotic and prebiotic vs placebo on psychological outcomes in patients with major depressive disorder: A randomized clinical trial

A Kazemi, AA Noorbala, K Azam, MH Eskandari… - Clinical Nutrition, 2019 - Elsevier
Background Disturbance in the equilibrium of the gut microbiota has been involved in the
pathophysiology of depression. Probiotics have the potential to healthfully modulate the gut …

A meta-analysis of the use of probiotics to alleviate depressive symptoms

QX Ng, C Peters, CYX Ho, DY Lim, WS Yeo - Journal of affective disorders, 2018 - Elsevier
Introduction Some preclinical and clinical studies have demonstrated the positive impact of
probiotic supplementation on depressive symptoms. This paper aims to provide an updated …

Effect of probiotic supplementation on gut microbiota in patients with major depressive disorders: A systematic review

QX Ng, YL Lim, CYL Yaow, WK Ng, J Thumboo… - Nutrients, 2023 - mdpi.com
There is accumulating evidence on the beneficial effects of probiotic supplementation for
patients with depressive disorders. However, prior reviews on the topic have largely focused …

[HTML][HTML] The efficacy, safety, and tolerability of probiotics on depression: clinical results from an open-label pilot study

CJK Wallace, RV Milev - Frontiers in psychiatry, 2021 - frontiersin.org
Background: A growing body of research has shown that consumption of probiotics can
improve symptoms associated with mood and anxiety disorders through activity of the gut …

Effect of probiotic interventions on depressive symptoms: A narrative review evaluating systematic reviews

I Nadeem, MZ Rahman… - Psychiatry and …, 2019 - Wiley Online Library
Depression is one of the most prevalent mental illnesses and is often associated with
various other medical disorders. Since the 1980s, the primary pharmacological treatment …

Clinical and metabolic response to probiotic administration in patients with major depressive disorder: a randomized, double-blind, placebo-controlled trial

G Akkasheh, Z Kashani-Poor, M Tajabadi-Ebrahimi… - Nutrition, 2016 - Elsevier
Objective We are aware of no study examining the effects of probiotic supplementation on
symptoms of depression, metabolic profiles, serum high-sensitivity C-reactive protein (hs …

Effect of probiotics on depressive symptoms: A meta-analysis of human studies

KK Goh, YW Liu, PH Kuo, YCE Chung, ML Lu… - Psychiatry …, 2019 - Elsevier
Accumulating data show that probiotics may be beneficial in reducing depressive symptoms.
We conducted an updated meta-analysis and evaluated the effects of probiotics on …

Effect of short-term, high-dose probiotic supplementation on cognition, related brain functions and BDNF in patients with depression: a secondary analysis of a …

E Schneider, JPK Doll, N Schweinfurth… - Journal of Psychiatry and …, 2023 - jpn.ca
Background: In major depressive disorder (MDD), cognitive dysfunctions strongly contribute
to functional impairments but are barely addressed in current therapies. Novel treatment …

Effect of prebiotics, probiotics, synbiotics on depression: results from a meta-analysis

Q Zhang, B Chen, J Zhang, J Dong, J Ma, Y Zhang… - BMC psychiatry, 2023 - Springer
Accumulating studies have shown the effects of gut microbiota management tools in
improving depression. We conducted a meta-analysis to evaluate the effects of prebiotics …

Effect of probiotics on depression: a systematic review and meta-analysis of randomized controlled trials

R Huang, K Wang, J Hu - Nutrients, 2016 - mdpi.com
It has been reported that gut probiotics play a major role in the bidirectional communication
between the gut and the brain. Probiotics may be essential to people with depression, which …