Phosphoinositides (PIs) are phospholipids derived from phosphatidylinositol. PIs are
regulated via reversible phosphorylation, which is directed by the opposing actions of PI …

Primary cilia are microtube-based organelles that extend from the cell surface and function
as biochemical and mechanical extracellular signal sensors. Primary cilia coordinate a …

Primary cilia are solitary signalling organelles projecting from the surface of most cell types.
Although the ciliary membrane is continuous with the plasma membrane it exhibits a unique …

How phosphoinositide metabolism is coupled to primary cilia physiology is poorly
understood. Reporting recently in Developmental Cell, Chávez et al.(2015) and Garcia …

Primary cilia are evolutionary conserved microtubule-based organelles that protrude from
the surface of most mammalian cells. Phosphoinositides (PI) are membrane-associated …

Phosphoinositides are low-abundant lipid signaling molecules that govern key cellular
processes including membrane trafficking, cytoskeletal rearrangement, and cell signaling to …

Phosphoinositides (PIs) have long been known to have important roles in cell signalling.
During the past decade, it has become clear that these lipids also act as constitutive signals …

The inositol phospholipids (PIs) comprise a family of eight species with different
combinations of phosphate groups arranged around the inositol ring. PIs are among the …

Phosphoinositides (PIs) are phospholipids that perform crucial cell functions, ranging from
cell migration and signaling to membrane trafficking, by serving as signposts of …

Phosphoinositides function as signaling precursors as well as regulators and scaffolds of
signaling molecules required for important cellular processes such as membrane trafficking …