YK Kim - Experimental & Molecular Medicine, 2022 - nature.com
RNA therapy refers to the treatment or prevention of diseases using RNA-based molecules. The recent advent of a series of effective messenger RNA-based vaccines in response to the …
A Curreri, D Sankholkar, S Mitragotri… - Bioengineering & …, 2023 - Wiley Online Library
Ribonucleic acid (RNA) therapeutics are being actively researched as a therapeutic modality in preclinical and clinical studies. They have become one of the most ubiquitously …
H Shin, SJ Park, Y Yim, J Kim, C Choi… - Advanced …, 2018 - Wiley Online Library
Recently, there have been significant advances in the field of RNA‐based therapeutics harnessing exogenous RNAs including small interfering RNA (siRNA), microRNA (miRNA) …
LY Zhou, Z Qin, YH Zhu, ZY He, T Xu - Current Gene Therapy, 2019 - ingentaconnect.com
Long-term research on various types of RNAs has led to further understanding of diverse mechanisms, which eventually resulted in the rapid development of RNA-based …
AA Seyhan - International Journal of Molecular Sciences, 2024 - mdpi.com
The discovery of the link between microRNAs (miRNAs) and a myriad of human diseases, particularly various cancer types, has generated significant interest in exploring their …
AF Christopher, RP Kaur, G Kaur, A Kaur… - … in clinical research, 2016 - journals.lww.com
MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate gene expression in diverse biological process. They act as intracellular mediators that are necessary for …
YK Kim - Chonnam medical journal, 2020 - ncbi.nlm.nih.gov
Recent studies identified diverse RNAs including noncoding RNAs and their various action mechanisms in the cells. These RNAs regulate a variety of cellular pathways and are …
The growing knowledge on several classes of non-coding RNAs (ncRNAs) and their different functional roles has aroused great interest in the scientific community. Beyond the …
Y Zhu, L Zhu, X Wang, H Jin - Cell death & disease, 2022 - nature.com
The growing understanding of RNA functions and their crucial roles in diseases promotes the application of various RNAs to selectively function on hitherto “undruggable” proteins …