Current updates on metabolites and its interlinked pathways as biomarkers for diabetic kidney disease: a systematic review

S Das, D Rajeswari, G Venkataraman, R Elumalai… - Translational …, 2023 - Elsevier
Diabetic kidney disease (DKD) is a major microvascular complication of diabetes mellitus
(DM) that poses a serious risk as it can lead to end-stage renal disease (ESRD). DKD is …

Metabolomic biomarkers in diabetic kidney diseases—A systematic review

Y Zhang, S Zhang, G Wang - Journal of Diabetes and its Complications, 2015 - Elsevier
Diabetic kidney disease (DKD) is generally characterized by increasing albuminuria in
diabetic patients; however, few biomarkers are available to facilitate early diagnosis of this …

Roles of gut microbial metabolites in diabetic kidney disease

Q Fang, N Liu, B Zheng, F Guo, X Zeng… - Frontiers in …, 2021 - frontiersin.org
Diabetes is a highly prevalent metabolic disease that has emerged as a global challenge
due to its increasing prevalence and lack of sustainable treatment. Diabetic kidney disease …

[HTML][HTML] Gut microbiota and its metabolites–molecular mechanisms and management strategies in diabetic kidney disease

ZH Mao, ZX Gao, DW Liu, ZS Liu, P Wu - Frontiers in Immunology, 2023 - frontiersin.org
Diabetic kidney disease (DKD) is one of the major microvascular complications of diabetes
mellitus and is also one of the serious risk factors in cardiovascular events, end-stage renal …

Clinical metabolomics characteristics of diabetic kidney disease: A meta‐analysis of 1875 cases with diabetic kidney disease and 4503 controls

Y Yuan, L Huang, L Yu, X Yan, S Chen… - Diabetes/Metabolism …, 2024 - Wiley Online Library
Abstract Aims Diabetic Kidney Disease (DKD), one of the major complications of diabetes, is
also a major cause of end‐stage renal disease. Metabolomics can provide a unique …

[HTML][HTML] Characteristics of serum metabolites and gut microbiota in diabetic kidney disease

B Zhang, Y Wan, X Zhou, H Zhang, H Zhao… - Frontiers in …, 2022 - frontiersin.org
Disturbance of circulating metabolites and disorders of the gut microbiota are involved in the
progression of diabetic kidney disease (DKD). However, there is limited research on the …

Quantitative, targeted analysis of gut microbiota derived metabolites provides novel biomarkers of early diabetic kidney disease in type 2 diabetes mellitus patients

L Balint, C Socaciu, AI Socaciu, A Vlad, F Gadalean… - Biomolecules, 2023 - mdpi.com
Diabetic kidney disease (DKD) is one of the most debilitating complications of type 2
diabetes mellitus (T2DM), as it progresses silently to end-stage renal disease (ESRD). The …

Harnessing metabolomics to describe the pathophysiology underlying progression in diabetic kidney disease

S Hasegawa, R Inagi - Current Diabetes Reports, 2021 - Springer
Abstract Purpose of Review Diabetic kidney disease (DKD), a leading cause of end-stage
kidney disease, is the result of metabolic network alterations in the kidney. Therefore …

Metabolomics as a tool for the early diagnosis and prognosis of diabetic kidney disease

PR Pereira, DF Carrageta, PF Oliveira… - Medicinal Research …, 2022 - Wiley Online Library
Diabetic kidney disease (DKD) is one of the most prevalent comorbidities of diabetes
mellitus and the leading cause of the end‐stage renal disease (ESRD). DKD results from …

Potential plasma metabolite biomarkers of diabetic nephropathy: Untargeted metabolomics study

OP Trifonova, DL Maslov, EE Balashova… - Journal of Personalized …, 2022 - mdpi.com
Diabetic nephropathy (DN) is one of the specific complications of diabetes mellitus and one
of the leading kidney-related disorders, often requiring renal replacement therapy. Currently …