Ursolic acid (UA): A metabolite with promising therapeutic potential

D Kashyap, HS Tuli, AK Sharma - Life sciences, 2016 - Elsevier
Plants are known to produce a variety of bioactive metabolites which are being used to cure
various life threatening and chronic diseases. The molecular mechanism of action of such …

Therapeutic potential of ursolic acid in cancer and diabetic neuropathy diseases

M Alam, S Ali, S Ahmed, AM Elasbali, M Adnan… - International journal of …, 2021 - mdpi.com
Ursolic acid (UA) is a pentacyclic triterpenoid frequently found in medicinal herbs and plants,
having numerous pharmacological effects. UA and its analogs treat multiple diseases …

Ursolic acid analogs as potential therapeutics for cancer

SS Panda, M Thangaraju, BL Lokeshwar - Molecules, 2022 - mdpi.com
Ursolic acid (UA) is a pentacyclic triterpene isolated from a large variety of vegetables, fruits
and many traditional medicinal plants. It is a structural isomer of Oleanolic Acid. The …

Ursolic acid-based derivatives as potential anti-cancer agents: An update

V Khwaza, OO Oyedeji, BA Aderibigbe - International journal of molecular …, 2020 - mdpi.com
Ursolic acid is a pharmacologically active pentacyclic triterpenoid derived from medicinal
plants, fruit, and vegetables. The pharmacological activities of ursolic acid have been …

Ursolic acid: A natural modulator of signaling networks in different cancers

S Zafar, K Khan, A Hafeez, M Irfan, M Armaghan… - Cancer Cell …, 2022 - Springer
Incidence rate of cancer is estimated to increase by 40% in 2030. Furthermore, the
development of resistance against currently available treatment strategies has contributed to …

Ursolic acid derivatives for pharmaceutical use: a patent review (2012-2016)

H Hussain, IR Green, I Ali, IA Khan, Z Ali… - Expert Opinion on …, 2017 - Taylor & Francis
ABSTRACT Introduction: Ursolic acid (UA), belongs to a group of pentacyclic triterpenoids
and is known to possess some very interesting biological properties. Protocols have been …

[HTML][HTML] Ursolic acid a promising candidate in the therapeutics of breast cancer: Current status and future implications

J Iqbal, BA Abbasi, R Ahmad, T Mahmood… - Biomedicine & …, 2018 - Elsevier
Breast cancer [BC] is the deadliest neoplasm in women globally and the second leading
cause of cancer associated deaths. Current treatment methods include chemotherapy …

Therapeutic potential of ursonic acid: comparison with ursolic acid

J Son, SY Lee - Biomolecules, 2020 - mdpi.com
Plants have been used as drugs to treat human disease for centuries. Ursonic acid (UNA) is
a naturally occurring pentacyclic triterpenoid extracted from certain medicinal herbs such as …

Ursolic acid: An anti‐and pro‐inflammatory triterpenoid

Y Ikeda, A Murakami, H Ohigashi - Molecular nutrition & food …, 2008 - Wiley Online Library
There is growing interest in the elucidation of the biological functions of triterpenoids,
ubiquitously distributed throughout the plant kingdom, some of which are used as anticancer …

Ursolic acid: An overview on its cytotoxic activities against breast and colorectal cancer cells

EWC Chan, CY Soon, JBL Tan, SK Wong… - Journal of integrative …, 2019 - Elsevier
Ursolic acid (UA) is a pentacyclic triterpene of the ursane type. As a common chemical
constituent among species of the family Lamiaceae, UA possesses a broad spectrum of …