Lymph nodes (LNs) occupy a critical position in initiating and augmenting immune
responses, both spatially and functionally. In cancer immunotherapy, tumor-specific …

Although cancer immunotherapy is a compelling approach against cancer, its effectiveness
is hindered by the challenge of generating a robust and durable immune response against …

In cancer, lymph nodes (LNs) coordinate tumor antigen presentation necessary for effective
antitumor immunity, both at the levels of local cellular interactions and tissue-level …

Vaccines are a promising immunotherapy that awakens the human immune system to inhibit
and eliminate cancer with fewer side effects compared with traditional radiotherapy and …

In situ cancer vaccines consisting of antigens and adjuvants are a promising cancer
treatment modality; however, the convenient manufacture of vaccines in vivo and their …

Nanoparticles, microparticles, and other biomaterials are advantageous in vaccination
because these materials provide opportunities to modulate specific characteristics of …

Tumor vaccines, a crucial immunotherapy, have gained growing interest because of their
unique capability to initiate precise anti-tumor immune responses and establish enduring …

Cancer vaccines hold promise as an immunotherapeutic modality based on their potential to
generate tumor antigen-specific T cell responses and long-lived antitumor responses …

Conspectus Development of vaccine technology that induces long lasting and potent
adaptive immune responses is of vital importance to combat emerging pathogens and to …

Recently approved cancer immunotherapies–including CAR-T cells and cancer vaccination,–
show great promise. However, these technologies are hindered by the complexity and cost …