Traumatic stress load and stressor reactivity score associated with accelerated gray matter maturation in youths indexed by normative models

TY Wong, TM Moore, J Seidlitz, KSL Yuen… - Molecular …, 2023 - nature.com
Understanding how traumatic stress affects typical brain development during adolescence is
critical to elucidate underlying mechanisms related to both maladaptive functioning and …

Early-life and pubertal stress differentially modulate grey matter development in human adolescents

A Tyborowska, I Volman, HCM Niermann… - Scientific reports, 2018 - nature.com
Animal and human studies have shown that both early-life traumatic events and ongoing
stress episodes affect neurodevelopment, however, it remains unclear whether and how …

The association between latent trauma and brain structure in children

HJ Jeong, EL Durham, TM Moore, RM Dupont… - Translational …, 2021 - nature.com
The developing brain is marked by high plasticity, which can lead to vulnerability to early life
stressors. Previous studies indicate that childhood maltreatment is associated with structural …

Structural brain patterns associated with traumatic stress resilience and susceptibility to mood and anxiety symptoms in youths

R Barzilay, AFG Rosen, TM Moore, DR Roalf… - Adversity and Resilience …, 2020 - Springer
Understanding biological mechanisms underlying traumatic stress resilience is critical and
can advance preventive psychiatry. Brain phenotypes of stress resilience have been …

Long‐term effects of childhood trauma subtypes on adult brain function

J Cai, J Li, D Liu, S Gao, Y Zhao, J Zhang… - Brain and …, 2023 - Wiley Online Library
Introduction Childhood trauma is prevalent in our society, whereas little is known about why
and how different forms of early traumatic experiences exert long‐term effects on differential …

[HTML][HTML] Experience-dependent associations between distinct subtypes of childhood trauma and brain function and architecture

J Li, G Zhang, J Wang, D Liu, C Wan… - … Imaging in Medicine …, 2022 - ncbi.nlm.nih.gov
Background Childhood trauma can alter brain-development trajectories and lead to a
greater risk of psychopathology developing in adulthood. For this reason, understanding …

Utility of the cumulative stress and mismatch hypotheses in understanding the neurobiological impacts of childhood abuse and recent stress in youth with emerging …

C Paquola, MR Bennett, SN Hatton… - Human brain …, 2017 - Wiley Online Library
Childhood abuse has an enduring impact on the brain's stress system. Whether the effects of
childhood abuse and adulthood stress are additive (cumulative stress hypothesis) or …

Association between traumatic stress load, psychopathology, and cognition in the Philadelphia Neurodevelopmental Cohort

R Barzilay, ME Calkins, TM Moore, DH Wolf… - Psychological …, 2019 - cambridge.org
BackgroundTraumatic stressors during childhood and adolescence are associated with
psychopathology, mostly studied in the context of post-traumatic stress disorder (PTSD) and …

Reduced hippocampal and medial prefrontal gray matter mediate the association between reported childhood maltreatment and trait anxiety in adulthood and predict …

AX Gorka, JL Hanson, SR Radtke, AR Hariri - Biology of mood & anxiety …, 2014 - Springer
Background The experience of early life stress is a consistently identified risk factor for the
development of mood and anxiety disorders. Preclinical research employing animal models …

Impact of early vs. late childhood early life stress on brain morphometrics

LM Baker, LM Williams, MS Korgaonkar… - Brain imaging and …, 2013 - Springer
Previous studies of early life trauma suggest that in addition to its emotional impact,
exposure to early life stress (ELS) is associated with alterations in brain structure. However …