Natural killer cells in antitumour adoptive cell immunotherapy

TJ Laskowski, A Biederstädt, K Rezvani - Nature Reviews Cancer, 2022 - nature.com
Natural killer (NK) cells comprise a unique population of innate lymphoid cells endowed with
intrinsic abilities to identify and eliminate virally infected cells and tumour cells. Possessing …

The application of natural killer cell immunotherapy for the treatment of cancer

K Rezvani, RH Rouce - Frontiers in immunology, 2015 - frontiersin.org
Natural killer (NK) cells are essential components of the innate immune system and play a
critical role in host immunity against cancer. Recent progress in our understanding of NK cell …

Exploring the NK cell platform for cancer immunotherapy

JA Myers, JS Miller - Nature reviews Clinical oncology, 2021 - nature.com
Natural killer (NK) cells are cytotoxic lymphocytes of the innate immune system that are
capable of killing virally infected and/or cancerous cells. Nearly 20 years ago, NK cell …

Challenges to the broad application of allogeneic natural killer cell immunotherapy of cancer

PR Kennedy, M Felices, JS Miller - Stem Cell Research & Therapy, 2022 - Springer
Natural killer (NK) cells are innate immune cells that recognize malignant cells through a
wide array of germline-encoded receptors. Triggering of activating receptors results in …

[HTML][HTML] Cancer immunotherapy based on natural killer cells: current progress and new opportunities

W Hu, G Wang, D Huang, M Sui, Y Xu - Frontiers in immunology, 2019 - frontiersin.org
Cancer immunotherapy has been firmly established as a new milestone for cancer therapy,
with the development of multiple immune cells as therapeutic tools. Natural killer (NK) cells …

[HTML][HTML] Emerging NK cell therapies for cancer and the promise of next generation engineering of iPSC-derived NK cells

S Maddineni, JL Silberstein… - … for Immunotherapy of …, 2022 - ncbi.nlm.nih.gov
Adoptive cell therapy is a rapidly advancing approach to cancer immunotherapy that seeks
to facilitate antitumor responses by introducing potent effector cells into the tumor …

Natural killer cell-based therapies targeting cancer: possible strategies to gain and sustain anti-tumor activity

CIM Dahlberg, D Sarhan, M Chrobok, AD Duru… - Frontiers in …, 2015 - frontiersin.org
Natural killer (NK) cells were discovered 40 years ago, by their ability to recognize and kill
tumor cells without the requirement of prior antigen exposure. Since then, NK cells have …

Natural born killers: NK cells in cancer therapy

SE Franks, B Wolfson, JW Hodge - Cancers, 2020 - mdpi.com
Cellular therapy has emerged as an attractive option for the treatment of cancer, and
adoptive transfer of chimeric antigen receptor (CAR) expressing T cells has gained FDA …

Natural killer cells: a promising immunotherapy for cancer

J Chu, F Gao, M Yan, S Zhao, Z Yan, B Shi… - Journal of translational …, 2022 - Springer
As a promising alternative platform for cellular immunotherapy, natural killer cells (NK) have
recently gained attention as an important type of innate immune regulatory cell. NK cells can …

Targeting natural killer cells for tumor immunotherapy

C Zhang, Y Hu, C Shi - Frontiers in immunology, 2020 - frontiersin.org
Natural killer (NK) cells are important innate cytotoxic lymphocytes with a rapid and efficient
capacity to recognize and kill tumor cells. In recent years, adoptive transfer of autologous-or …