Ten years of extracellular matrix proteomics: accomplishments, challenges, and future perspectives
A Naba - Molecular & Cellular Proteomics, 2023 - ASBMB
The extracellular matrix (ECM) is a complex assembly of hundreds of proteins forming the
architectural scaffold of multicellular organisms. In addition to its structural role, the ECM …
architectural scaffold of multicellular organisms. In addition to its structural role, the ECM …
Exploring the extracellular matrix in health and disease using proteomics
IN Taha, A Naba - Essays in biochemistry, 2019 - portlandpress.com
The extracellular matrix (ECM) is a complex assembly of hundreds of proteins that
constitutes the scaffold of multicellular organisms. In addition to providing architectural and …
constitutes the scaffold of multicellular organisms. In addition to providing architectural and …
Defining the extracellular matrix using proteomics
A Byron, JD Humphries… - International journal of …, 2013 - Wiley Online Library
The cell microenvironment has a profound influence on the behaviour, growth and survival
of cells. The extracellular matrix (ECM) provides not only mechanical and structural support …
of cells. The extracellular matrix (ECM) provides not only mechanical and structural support …
[HTML][HTML] The extracellular matrix: Tools and insights for the “omics” era
The extracellular matrix (ECM) is a fundamental component of multicellular organisms that
provides mechanical and chemical cues that orchestrate cellular and tissue organization …
provides mechanical and chemical cues that orchestrate cellular and tissue organization …
Characterization of the extracellular matrix of normal and diseased tissues using proteomics
A Naba, OMT Pearce, A Del Rosario… - Journal of proteome …, 2017 - ACS Publications
The extracellular matrix (ECM) is a complex meshwork of insoluble fibrillar proteins and
signaling factors interacting together to provide architectural and instructional cues to the …
signaling factors interacting together to provide architectural and instructional cues to the …
MatrisomeDB: the ECM-protein knowledge database
The extracellular matrix (ECM) is a complex and dynamic meshwork of cross-linked proteins
that supports cell polarization and functions and tissue organization and homeostasis. Over …
that supports cell polarization and functions and tissue organization and homeostasis. Over …
Enrichment of extracellular matrix proteins from tissues and digestion into peptides for mass spectrometry analysis
A Naba, KR Clauser, RO Hynes - JoVE (Journal of Visualized …, 2015 - jove.com
The extracellular matrix (ECM) is a complex meshwork of cross-linked proteins that provides
biophysical and biochemical cues that are major regulators of cell proliferation, survival …
biophysical and biochemical cues that are major regulators of cell proliferation, survival …
MatrisomeDB 2.0: 2023 updates to the ECM-protein knowledge database
X Shao, CD Gomez, N Kapoor… - Nucleic acids …, 2023 - academic.oup.com
The extracellular matrix (ECM) is a complex assembly of proteins that constitutes the scaffold
organizing cells, tissues, and organs. Over the past decade, mass-spectrometry-based …
organizing cells, tissues, and organs. Over the past decade, mass-spectrometry-based …
The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices
The extracellular matrix (ECM) is a complex meshwork of cross-linked proteins providing
both biophysical and biochemical cues that are important regulators of cell proliferation …
both biophysical and biochemical cues that are important regulators of cell proliferation …
The cancer matrisome: From comprehensive characterization to biomarker discovery
AM Socovich, A Naba - Seminars in cell & developmental biology, 2019 - Elsevier
Tumor progression and dissemination critically depend on support from the tumor
microenvironment, the ensemble of cellular and acellular components surrounding and …
microenvironment, the ensemble of cellular and acellular components surrounding and …