[HTML][HTML] Characterising sex differences of autosomal DNA methylation in whole blood using the Illumina EPIC array
Background Sex differences are known to play a role in disease aetiology, progression and
outcome. Previous studies have revealed autosomal epigenetic differences between males …
outcome. Previous studies have revealed autosomal epigenetic differences between males …
[HTML][HTML] Characterization of whole-genome autosomal differences of DNA methylation between men and women
P Singmann, D Shem-Tov, S Wahl, H Grallert… - Epigenetics & …, 2015 - Springer
Background Disease risk and incidence between males and females reveal differences, and
sex is an important component of any investigation of the determinants of phenotypes or …
sex is an important component of any investigation of the determinants of phenotypes or …
Autosomal sex-associated co-methylated regions predict biological sex from DNA methylation
E Gatev, AM Inkster, GL Negri, C Konwar… - Nucleic Acids …, 2021 - academic.oup.com
Sex is a modulator of health that has been historically overlooked in biomedical research.
Recognizing this knowledge gap, funding agencies now mandate the inclusion of sex as a …
Recognizing this knowledge gap, funding agencies now mandate the inclusion of sex as a …
[HTML][HTML] Association of DNA methylation with age, gender, and smoking in an Arab population
SB Zaghlool, M Al-Shafai, WA Al Muftah, P Kumar… - Clinical …, 2015 - Springer
Background Modification of DNA by methylation of cytosines at CpG dinucleotides is a
widespread phenomenon that leads to changes in gene expression, thereby influencing and …
widespread phenomenon that leads to changes in gene expression, thereby influencing and …
[HTML][HTML] Sex differences in DNA methylation assessed by 450 K BeadChip in newborns
Background DNA methylation is an important epigenetic mark that can potentially link early
life exposures to adverse health outcomes later in life. Host factors like sex and age strongly …
life exposures to adverse health outcomes later in life. Host factors like sex and age strongly …
[HTML][HTML] Genome-wide identification of inter-individually variable DNA methylation sites improves the efficacy of epigenetic association studies
Epigenome-wide association studies, which searches for blood-based DNA methylation
signatures associated with environmental exposures and/or disease susceptibilities, is a …
signatures associated with environmental exposures and/or disease susceptibilities, is a …
[HTML][HTML] Meta-analysis of human methylation data for evidence of sex-specific autosomal patterns
Background Several individual studies have suggested that autosomal CpG methylation
differs by sex both in terms of individual CpG sites and global autosomal CpG methylation …
differs by sex both in terms of individual CpG sites and global autosomal CpG methylation …
[HTML][HTML] Array-based DNA methylation profiling reveals peripheral blood differential methylation in male infertility
Objective To study peripheral blood DNA differential methylation in oligozoospermic infertile
men in comparison with normozoospermic fertile controls. Design Case-control study …
men in comparison with normozoospermic fertile controls. Design Case-control study …
[HTML][HTML] Genetic analysis of DNA methylation and gene expression levels in whole blood of healthy human subjects
KR van Eijk, S de Jong, MPM Boks, T Langeveld… - BMC genomics, 2012 - Springer
Background The predominant model for regulation of gene expression through DNA
methylation is an inverse association in which increased methylation results in decreased …
methylation is an inverse association in which increased methylation results in decreased …
Associations between infant sex and DNA methylation across umbilical cord blood, artery, and placenta samples
ABSTRACT DNA methylation (DNAm) is vulnerable to dysregulation by environmental
exposures during epigenetic reprogramming that occurs in embryogenesis. Sexual …
exposures during epigenetic reprogramming that occurs in embryogenesis. Sexual …