Glial glutamate transporter EAAT2 plays a major role in glutamate clearance in synaptic
clefts. Several lines of evidence indicate that strategies designed to increase EAAT2 …

Glutamate is the primary excitatory amino acid neurotransmitter in the CNS. The
concentration of glutamate in the synaptic cleft is tightly controlled by interplay between …

Dysfunction of excitatory amino acid transporters (EAATs) has been implicated in the
pathogenesis of various neurological disorders, such as stroke, brain trauma, epilepsy, and …

Abstract l‐glutamate is the predominant excitatory neurotransmitter in the CNS and has a
central role in a variety of brain functions. The termination of glutamate neurotransmission by …

Excitotoxicity has been implicated as the mechanism of neuronal damage resulting from
acute insults such as stroke, epilepsy, and trauma, as well as during the progression of adult …

Glutamate is the predominant excitatory amino acid neurotransmitter in the mammalian
central nervous system (CNS). Glutamate transporter EAAT2/GLT-1 is the physiologically …

Glutamate is the predominant excitatory neurotransmitter in the central nervous system.
Excitatory amino acid transporter 2 (EAAT2) is primarily responsible for clearance of …

Glutamate is an essential excitatory neurotransmitter regulating brain functions. Excitatory
amino acid transporter (EAAT)‐2 is one of the major glutamate transporters expressed …

Glutamatergic systems play a critical role in cognitive functions and are known to be
defective in Alzheimer's disease (AD) patients. Previous literature has indicated that glial …

Dysfunction of excitatory amino acid transporters (EAATs) has been implicated in the
pathogenesis of various neurological disorders, such as stroke, brain trauma, epilepsy, and …