Potent SARS-CoV-2 neutralizing antibodies with therapeutic effects in two animal models

M Takeshita, H Fukuyama, K Kamada, T Matsumoto… - Iscience, 2022 - cell.com
The use of therapeutic neutralizing antibodies against SARS-CoV-2 infection has been
highly effective. However, there remain few practical antibodies against viruses that are …

Potent neutralizing anti-SARS-CoV-2 human antibodies cure infection with SARS-CoV-2 variants in hamster model

M Imbrechts, W Maes, L Ampofo, N Van den Berghe… - Iscience, 2022 - cell.com
Treatment with neutralizing monoclonal antibodies (mAbs) against severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) contributes to COVID-19 management …

[HTML][HTML] Characterization of neutralizing antibodies from a SARS-CoV-2 infected individual

E Seydoux, LJ Homad, AJ MacCamy, KR Parks… - BioRxiv, 2020 - ncbi.nlm.nih.gov
B cells specific for the SARS-CoV-2 S envelope glycoprotein spike were isolated from a
COVID-19-infected subject using a stabilized spike-derived ectodomain (S2P) twenty-one …

Broadly neutralizing antibodies to SARS-CoV-2 and other human coronaviruses

Y Chen, X Zhao, H Zhou, H Zhu, S Jiang… - Nature Reviews …, 2023 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a recently emerged
pathogenic human coronavirus that belongs to the sarbecovirus lineage of the genus …

Neutralizing antibodies for the treatment of COVID-19

S Jiang, X Zhang, Y Yang, PJ Hotez, L Du - Nature biomedical …, 2020 - nature.com
Neutralizing antibodies for the treatment of COVID-19 | Nature Biomedical Engineering Skip to
main content Thank you for visiting nature.com. You are using a browser version with limited …

The development of a rapid, high-throughput neutralization assay using a SARS-CoV-2 reporter

R Suzuki, A Kamiyama, H Ito, K Kawashiro… - Journal of Virological …, 2024 - Elsevier
Many methods have been developed to measure the neutralizing capacity of antibodies to
SARS-CoV-2. However, these methods are low throughput and can be difficult to quickly …

Analysis of a SARS-CoV-2-infected individual reveals development of potent neutralizing antibodies with limited somatic mutation

E Seydoux, LJ Homad, AJ MacCamy, KR Parks… - Immunity, 2020 - cell.com
Antibody responses develop following SARS-CoV-2 infection, but little is known about their
epitope specificities, clonality, binding affinities, epitopes, and neutralizing activity. We …

Comparison of four SARS-CoV-2 neutralization assays

L Riepler, A Rössler, A Falch, A Volland, W Borena… - Vaccines, 2020 - mdpi.com
Neutralizing antibodies are a major correlate of protection for many viruses including the
novel coronavirus SARS-CoV-2. Thus, vaccine candidates should potently induce …

Potent mouse monoclonal antibodies that block SARS-CoV-2 infection

Y Guo, A Kawaguchi, M Takeshita, T Sekiya… - Journal of Biological …, 2021 - ASBMB
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), has developed into a global pandemic since its first outbreak …

Evaluation of a panel of therapeutic antibody clinical candidates for efficacy against SARS-CoV-2 in Syrian hamsters

Y Cong, EM Mucker, DL Perry, S Dixit, E Kollins… - Antiviral Research, 2023 - Elsevier
The COVID-19 pandemic spurred the rapid development of a range of therapeutic antibody
treatments. As part of the US government's COVID-19 therapeutic response, a research …