Frizzled receptors in development and disease
Frizzled proteins are the principal receptors for the Wnt family of ligands. They mediate
canonical Wnt signaling together with Lrp5 and Lrp6 coreceptors. In conjunction with Celsr …
canonical Wnt signaling together with Lrp5 and Lrp6 coreceptors. In conjunction with Celsr …
Frizzled signaling and the developmental control of cell polarity
JM Shulman, N Perrimon, JD Axelrod - Trends in Genetics, 1998 - cell.com
Within the last three years, Frizzled receptors have risen from obscurity to celebrity status
owing to their functional identification as receptors for the ubiquitous family of secreted Wnt …
owing to their functional identification as receptors for the ubiquitous family of secreted Wnt …
Wnt-frizzled signaling to G-protein-coupled effectors
HY Wang, CC Malbon - Cellular and Molecular Life Sciences CMLS, 2004 - Springer
Wnt proteins signal via cell surface receptors termed Frizzleds. Frizzleds display many
properties characteristic of members of the superfamily of G-protein-coupled receptors …
properties characteristic of members of the superfamily of G-protein-coupled receptors …
Expression of Frizzled5, Frizzled7, and Frizzled10 during early mouse development and interactions with canonical Wnt signaling
CR Kemp, E Willems, D Wawrzak… - … dynamics: an official …, 2007 - Wiley Online Library
The Wnt signaling pathway, conserved throughout the animal kingdom, has been shown to
be involved in a wide range of biological processes, from axis induction in the early embryo …
be involved in a wide range of biological processes, from axis induction in the early embryo …
Multiplicity of the interactions of Wnt proteins and their receptors
A Kikuchi, H Yamamoto, S Kishida - Cellular signalling, 2007 - Elsevier
Wnts are secreted proteins that are essential for a wide array of developmental and
physiological processes. They signal across the plasma membranes by interacting with …
physiological processes. They signal across the plasma membranes by interacting with …
[HTML][HTML] Expression of Xfz3, a Xenopus frizzled family member, is restricted to the early nervous system
DL Shi, C Goisset, JC Boucaut - Mechanisms of development, 1998 - Elsevier
Recent advances in analyzing wnt signaling have provided evidence that frizzled proteins
can function as wnt receptors. We have identified Xfz3, a Xenopus frizzled family member …
can function as wnt receptors. We have identified Xfz3, a Xenopus frizzled family member …
Frizzled 2 and frizzled 7 function redundantly in convergent extension and closure of the ventricular septum and palate: evidence for a network of interacting genes
Frizzled (Fz) 2 and Fz7, together with Fz1, form a distinct subfamily within the Frizzled family
of Wnt receptors. Using targeted gene deletion, we show that: Fz7−/− mice exhibit tail …
of Wnt receptors. Using targeted gene deletion, we show that: Fz7−/− mice exhibit tail …
Wnt signaling
R Nusse - Cold Spring Harbor perspectives in biology, 2012 - cshperspectives.cshlp.org
Wnt Signaling Cold Spring Harbor Perspectives in Biology Skip to main page content HOME
ABOUT SUBJECT COLLECTIONS ARCHIVE SUBSCRIBE ADVERTISE ALERTS FEEDBACK …
ABOUT SUBJECT COLLECTIONS ARCHIVE SUBSCRIBE ADVERTISE ALERTS FEEDBACK …
Secreted Frizzled‐related proteins: searching for relationships and patterns
SE Jones, C Jomary - Bioessays, 2002 - Wiley Online Library
Abstract Secreted Frizzled‐related proteins (SFRPs) are modulators of the intermeshing
pathways in which signals are transduced by Wnt ligands through Frizzled (Fz) membrane …
pathways in which signals are transduced by Wnt ligands through Frizzled (Fz) membrane …
Subcellular localization of frizzled receptors, mediated by their cytoplasmic tails, regulates signaling pathway specificity
J Wu, TJ Klein, M Mlodzik - PLoS biology, 2004 - journals.plos.org
The Frizzled (Fz; called here Fz1) and Fz2 receptors have distinct signaling specificities
activating either the canonical Wnt/β-catenin pathway or Fz/planar cell polarity (PCP) …
activating either the canonical Wnt/β-catenin pathway or Fz/planar cell polarity (PCP) …