Disrupted salience network functional connectivity and white-matter microstructure in persons at risk for psychosis: findings from the LYRIKS study

C Wang, F Ji, Z Hong, JS Poh, R Krishnan… - Psychological …, 2016 - cambridge.org
BackgroundSalience network (SN) dysconnectivity has been hypothesized to contribute to
schizophrenia. Nevertheless, little is known about the functional and structural …

[HTML][HTML] Salience network glutamate and brain connectivity in medication-naïve first episode patients–A multimodal magnetic resonance spectroscopy and resting …

JO Maximo, F Briend, WP Armstrong, NV Kraguljac… - NeuroImage: Clinical, 2021 - Elsevier
Background Salience network (SN) connectivity is altered in schizophrenia, but the
pathophysiological origin remains poorly understood. The goal of this multimodal …

Aberrant functional connectivity within the salience network is related to cognitive deficits and disorganization in psychosis

LC Schiwy, CG Forlim, DJ Fischer, S Kühn… - Schizophrenia …, 2022 - Elsevier
In schizophrenia and schizoaffective disorder cognitive deficits are a reliable characteristic
predicting a poor functional outcome. It has been theorized that both the default mode …

Aberrant resting-state functional connectivity of salience network in first-episode schizophrenia

H Huang, Z Botao, Y Jiang, Y Tang, T Zhang… - Brain imaging and …, 2020 - Springer
The disruption of salience network (SN) has been consistently found in patients with
schizophrenia and thought to give rise to specific symptoms. However, the functional …

Resting state functional hyperconnectivity within a triple network model in paranoid schizophrenia

R Krishnadas, S Ryali, T Chen, L Uddin, K Supekar… - The Lancet, 2014 - thelancet.com
Background Three large-scale intrinsic connectivity brain networks, the salience network
(SN), the central executive network (CEN), and the default mode network (DMN), have …

The concept of salience network dysfunction in schizophrenia: from neuroimaging observations to therapeutic opportunities

L Palaniyappan, TP White… - Current topics in medicinal …, 2012 - ingentaconnect.com
A large body of neuroimaging literature suggests that distributed regions in the brain form
coordinated largescale networks that show reliable patterns of connectivity when observed …

Morphological and functional abnormalities of salience network in the early-stage of paranoid schizophrenia

W Pu, L Li, H Zhang, X Ouyang, H Liu, J Zhao, L Li… - Schizophrenia …, 2012 - Elsevier
A salience network (SN), mainly composed of the anterior insula (AI) and anterior cingulate
cortex (ACC), has been suggested to play an important role in salience attribution which has …

Aberrant intra-salience network dynamic functional connectivity impairs large-scale network interactions in schizophrenia

X Wang, W Zhang, Y Sun, M Hu, A Chen - Neuropsychologia, 2016 - Elsevier
Aberrant functional interactions between several large-scale networks, especially the central
executive network (CEN), the default mode network (DMN) and the salience network (SN) …

Dysregulated brain dynamics in a triple-network saliency model of schizophrenia and its relation to psychosis

K Supekar, W Cai, R Krishnadas, L Palaniyappan… - Biological …, 2019 - Elsevier
Background Schizophrenia is a highly disabling psychiatric disorder characterized by a
range of positive “psychosis” symptoms. However, the neurobiology of psychosis and …

Effective connectivity between major nodes of the limbic system, salience and frontoparietal networks differentiates schizophrenia and mood disorders from healthy …

S Kandilarova, DS Stoyanov, R Paunova… - Journal of Personalized …, 2021 - mdpi.com
This study was conducted to examine whether there are quantitative or qualitative
differences in the connectome between psychiatric patients and healthy controls and to …