An increase in fat mass is considered to be an important risk factor for the worldwide
increase in type 2 diabetes and cardiovascular disease. However, for a given fat mass, there …

Findings from epidemiological studies over the past 30 years have shown that visceral
adipose tissue, accurately measured by CT or MRI, is an independent risk marker of …

Obesity increases the risks of developing cardiovascular and metabolic diseases and
degrades quality of life, ultimately increasing the risk of death. However, not all forms of …

Although type 1 diabetes is traditionally considered a disease of lean people, overweight
and obesity are becoming increasingly more common in individuals with type 1 diabetes …

This review focuses on the human genetics, epidemiology, and molecular pathophysiology
of sex differences in central obesity, adipose distribution, and related cardiometabolic …

Epidemiological, clinical, and mechanistic preclinical studies conducted in the field of
cardiovascular medicine have led to remarkable progress in our understanding of …

Cardiometabolic diseases are one of the leading causes for disability and mortality in the
Western world. The prevalence of these chronic diseases is expected to rise even further in …

A BMI in the normal range associates with a decreased risk of cardiometabolic disease and
all-cause mortality. However, not all subjects in this BMI range have this low risk. Compared …

Obesity is linked to numerous comorbidities that include, but are not limited to, glucose
intolerance, insulin resistance, dyslipidemia, and cardiovascular disease. Current evidence …

The burden of obesity has increased globally over the last few decades and its association
with insulin resistance and related cardio-metabolic problems have adversely affected our …