Abstract Interferon regulatory factor 4 (IRF4) is a member of IRF family of transcription factors
which mainly regulates the transcription of IFN. IRF4 is restrictively expressed in immune …

The transcription factor interferon regulatory factor-5 (IRF5) plays an important role in innate
immune responses via the TLR-MyD88 (Toll-like receptor-myeloid differentiation primary …

Systemic lupus erythematosus (SLE) is a severe multi-system autoimmune disease,
whereas interferon regulatory factor (IRF) 5 belongs to the family of transcription factors that …

Systemic lupus erythematosus is an autoimmune disease attributing to a combination of
genetic and environmental factors. Abnormal expression/function of type I interferons has …

Recently much attention was attracted to the importance of the type I interferon pathway in
the initiation and development of the autoimmune disease systemic lupus erythematosus …

The transcription factor IRF5 has been implicated as a therapeutic target for the autoimmune
disease systemic lupus erythematosus (SLE). However, IRF5 activation status during the …

As a member of the IRF family of transcription factors, interferon regulatory factor 4 (IRF4) is
expressed in most cell types of the immune system. Recent findings suggest that IRF4 is …

The transcription factor interferon regulatory factor 5 (IRF5) is a central mediator of innate
and adaptive immunity. Genetic variations within IRF5 associate with risk for systemic lupus …

Interferon regulatory factor 5 (IRF5) has been described as an important factor in regulating
inflammatory response and a key transcription factor in the immune system. In antiviral …

The transcription factor interferon regulatory factor 5 (IRF5) has previously been implicated
in systemic lupus erythematosus (SLE) development, but its precise role in this process is …