Maternal serum interleukin-6, C-reactive protein, and matrix metalloproteinase-9 concentrations as risk factors for preterm birth< 32 weeks and adverse neonatal …

Y Sorokin, R Romero, L Mele… - American journal of …, 2010 - thieme-connect.com
Elevated concentrations of interleukin-6 (IL-6), C-reactive protein (CRP), and matrix
metalloproteinase-9 (MMP-9) in fetal and neonatal compartments have been associated …

Mid-trimester maternal plasma cytokines and CRP as predictors of spontaneous preterm birth

MS Kramer, SR Kahn, RW Platt, J Genest, MF Chen… - Cytokine, 2010 - Elsevier
Most previous studies of maternal cytokines and preterm birth have analyzed immunologic
biomarkers after the onset of labor or membrane rupture; fewer have examined the systemic …

The fetal inflammatory response syndrome

R Gomez, R Romero, F Ghezzi, BH Yoon… - American journal of …, 1998 - Elsevier
OBJECTIVE: The objective of this study was to determine the frequency and clinical
significance of a systemic inflammatory response as defined by an elevated plasma …

Second trimester maternal plasma levels of cytokines IL-1Ra, Il-6 and IL-10 and preterm birth

RJ Ruiz, N Jallo, C Murphey, CN Marti… - Journal of …, 2012 - nature.com
Objective: To examine the interaction of the cytokines interleukin-1 receptor antagonist (IL)-
1Ra, IL-6 and IL-10 to predict preterm birth (PTB) in pregnant Hispanic women (n= 470) …

Maternal serum interleukin-6 concentration as a marker for impending preterm delivery

AP Murtha, PC Greig, CE JIMMERSON… - Obstetrics & …, 1998 - journals.lww.com
Methods: Blood samples were collected from 130 gravidas at 22-34 weeks' gestation. The
study group consisted of 89 women evaluated for preterm contractions or premature rupture …

Elevated second-trimester amniotic fluid interleukin-6 levels predict preterm delivery

KD Wenstrom, WW Andrews, JC Hauth… - American journal of …, 1998 - Elsevier
OBJECTIVE: Our purpose was to determine whether early second-trimester amniotic fluid
interleukin-6 levels predict delivery before 34 weeks' gestation. STUDY DESIGN: We used …

Blood protein profiles of infants born before 28 weeks differ by pregnancy complication

TF McElrath, RN Fichorova, EN Allred, JL Hecht… - American journal of …, 2011 - Elsevier
OBJECTIVE: Disorders that lead to preterm delivery influence the fetal inflammatory
response. STUDY DESIGN: We calculated odds ratios of elevated concentrations of 25 …

Maternal serum interleukin-6 during pregnancy and during term and preterm labor

PC Greig, AP Murtha, CJ Jimmerson, WNP Herbert… - Obstetrics & …, 1997 - Elsevier
Objective: To determine the normal concentrations of maternal serum interleukin-6 during
the second and third trimesters of pregnancy and the different stages of term and preterm …

Umbilical cord plasma interleukin-6 concentrations in preterm infants and risk of neonatal morbidity

AR Goepfert, WW Andrews, W Carlo… - American journal of …, 2004 - Elsevier
OBJECTIVE: This study was undertaken to evaluate the association between umbilical cord
interleukin-6 (IL-6) levels and neonatal morbidity in infants born at less than 32 weeks' …

Elevated amniotic fluid interleukin‐6 levels during the early second trimester are associated with greater risk of subsequent preterm delivery

A Ghidini, CB Jenkins, CY Spong… - American Journal of …, 1997 - Wiley Online Library
PROBLEM: Subclinical intra‐amniotic infection is often associated with preterm delivery and
may precede it by several weeks. We tested the hypothesis that Interleukin‐6 (IL‐6) may be …