Single-gene causes of congenital anomalies of the kidney and urinary tract (CAKUT) in humans

A Vivante, S Kohl, DY Hwang, GC Dworschak… - Pediatric …, 2014 - Springer
Congenital anomalies of the kidney and urinary tract (CAKUT) cover a wide range of
structural malformations that result from defects in the morphogenesis of the kidney and/or …

Novel insights into the pathogenesis of monogenic congenital anomalies of the kidney and urinary tract

AT van der Ven, A Vivante… - Journal of the American …, 2018 - journals.lww.com
Congenital anomalies of the kidneys and urinary tract (CAKUT) comprise a large spectrum
of congenital malformations ranging from severe manifestations, such as renal agenesis, to …

Whole-exome sequencing identifies causative mutations in families with congenital anomalies of the kidney and urinary tract

AT Van Der Ven, DM Connaughton, H Ityel… - Journal of the …, 2018 - journals.lww.com
Background Congenital anomalies of the kidney and urinary tract (CAKUT) are the most
prevalent cause of kidney disease in the first three decades of life. Previous gene panel …

Congenital anomalies of the kidney and urinary tract: a genetic disorder?

IV Yosypiv - International journal of nephrology, 2012 - Wiley Online Library
Congenital anomalies of the kidney and urinary tract (CAKUTs) occur in 3–6 per 1000 live
births, account for the most cases of pediatric end‐stage kidney disease (ESKD), and …

The genetics and pathogenesis of CAKUT

CM Kolvenbach, S Shril, F Hildebrandt - Nature Reviews Nephrology, 2023 - nature.com
Congenital anomalies of the kidney and urinary tract (CAKUT) comprise a large variety of
malformations that arise from defective kidney or urinary tract development and frequently …

Developmental genetics and congenital anomalies of the kidney and urinary tract

N Uy, K Reidy - Journal of pediatric genetics, 2016 - thieme-connect.com
Congenital anomalies of the kidney and urinary tract (CAKUT) are common birth defects and
the leading cause of end-stage renal disease in children. There is a wide spectrum of renal …

Novel perspectives for investigating congenital anomalies of the kidney and urinary tract (CAKUT)

KY Renkema, PJ Winyard… - Nephrology dialysis …, 2011 - academic.oup.com
Congenital anomalies of the kidney and urinary tract (CAKUT) are the commonest cause of
chronic kidney disease in children. Structural anomalies within the CAKUT spectrum include …

The genetic basis of congenital anomalies of the kidney and urinary tract

M Kagan, O Pleniceanu, A Vivante - Pediatric Nephrology, 2022 - Springer
During the past decades, remarkable progress has been made in our understanding of the
molecular basis of kidney diseases, as well as in the ability to pinpoint disease-causing …

Molecular causes of congenital anomalies of the kidney and urinary tract (CAKUT)

S Kohl, S Habbig, LT Weber, MC Liebau - Molecular and cellular …, 2021 - Springer
Congenital anomalies of the kidney and urinary tract (CAKUT) occur in 0.5–1/100 newborns
and as a group they represent the most frequent cause for chronic kidney failure in children …

Genetic, environmental, and epigenetic factors involved in CAKUT

N Nicolaou, KY Renkema, EMHF Bongers… - Nature Reviews …, 2015 - nature.com
Congenital anomalies of the kidney and urinary tract (CAKUT) refer to a spectrum of
structural renal malformations and are the leading cause of end-stage renal disease in …