Inborn errors of immunity (IEI) are a heterogeneous group of disorders, mainly resulting from
mutations in genes associated with immunoregulation and immune host defense. These …

abstract Monogenic diseases of the immune system, also known as inborn errors of
immunity (IEIs), are caused by single-gene mutations and result in immune deficiency and …

Introduction: Inborn errors of immunity (IEIs) are rare inherited disorders with a broad
spectrum of manifestations. Here, we aimed to delineate the atopy burden in a cohort of …

Background Monogenic conditions that disrupt proper development and/or function of the
immune system are termed inborn errors of immunity (IEIs), also known as primary …

Recent advances in the field of inborn errors of immunity (IEIs) have been wide in scope,
including progress in mechanisms of disease, diagnosis, and management. New gene …

Atopic disorders, including atopic dermatitis, food and environmental allergies, and asthma,
are increasingly prevalent diseases. Atopic disorders are often associated with eosinophilia …

Around 20% of all children worldwide suffer from atopic dermatitis. Therefore, eczematous
skin lesions and elevated serum immunoglobulin E (IgE) levels are common findings. Inborn …

Inborn errors of immunity are traditionally best known for enhancing susceptibility to
infections. However, allergic inflammation, among other types of immune dysregulation …

Elevated immunoglobulin E (IgE) is a hallmark of allergic diseases. However, high IgE levels
also occur in a number of other infectious and noninfectious diseases. In most cases …

Inborn errors of immunity (IEIs) are a group of conditions whereby parts of the immune
system are missing or dysfunctional. Once thought to primarily be a pediatric disorder, it is …