Malaria remains a major global health challenge. Appropriate use of current antimalarial
tools has reduced the disease burden, but morbidity and mortality remain unacceptably …

Malaria remains one of the most prevalent tropical and infectious diseases in the world, with
an estimated more than 200 million clinical cases every year. In recent years, the mosquito …

New interventions are needed to reduce morbidity and mortality associated with malaria, as
well as to accelerate elimination and eventual eradication. Interventions that can break the …

Transmission-blocking vaccines (TBVs) utilize Plasmodium sexual stage proteins to induce
antibodies that prevent parasites from infecting blood-fed mosquitoes. This type of vaccine …

Malaria kills more than 600 000 people yearly, mainly children, and eradication is a global
priority. Malaria transmission-blocking vaccines are advancing in clinical trials, and …

The recently announced call for malaria eradication represents a new page in the history of
this disease. This has been triggered by remarkable reductions in malaria resulting from …

Remarkable progress has been made in coordinated malaria control efforts with substantial
reductions in malaria-associated deaths and morbidity achieved through mass …

The rapid spread of mosquito resistance to currently available insecticides, and the current
lack of an efficacious malaria vaccine are among many challenges that affect large-scale …

Following the cessation of the global malaria eradication initiative in the 1970s, the prime
objective of malarial intervention has been to reduce morbidity and mortality. This motivated …

Malaria is still a leading cause of morbidity and mortality in human populations. Problems,
including drug-resistant parasites and insecticide resistant mosquitoes, ensure the …