From ancient to emerging infections: the odyssey of viruses in the male genital tract

A Le Tortorec, G Matusali, D Mahé… - Physiological …, 2020 - journals.physiology.org
The male genital tract (MGT) is the target of a number of viral infections that can have
deleterious consequences at the individual, offspring, and population levels. These …

Human Sertoli cells support high levels of Zika virus replication and persistence

A Kumar, J Jovel, J Lopez-Orozco, D Limonta… - Scientific reports, 2018 - nature.com
Zika virus is a teratogenic mosquito-transmitted flavivirus that is associated with birth defects
in newborns and Guillain–Barré syndrome in adults. The virus can also be sexually …

[HTML][HTML] Focus: infectious diseases: Zika virus and sexual transmission: a new route of transmission for mosquito-borne flaviviruses

AK Hastings, E Fikrig - The Yale journal of biology and medicine, 2017 - ncbi.nlm.nih.gov
Beginning in 2015, concern over a new global epidemic has spread in the media,
governmental agencies, legislative bodies and the public at large. This newly emerging …

Viral threat to male fertility

W Liu, R Han, H Wu, D Han - Andrologia, 2018 - Wiley Online Library
The detrimental effects of Zika virus (ZIKV) infection on mouse testicular functions have
reminded a viral threat to male fertility. A broad range of virus families has tropism for male …

Virus in semen and the risk of sexual transmission

H Feldmann - New England Journal of Medicine, 2018 - Mass Medical Soc
Sexual contact is the primary route of human transmission for sexually transmitted infections
(STIs). Traditional STIs are caused by a variety of pathogens, and classic examples of STIs …

Human testicular organoid system as a novel tool to study Zika virus pathogenesis

DP Strange, NP Zarandi, G Trivedi, A Atala… - Emerging microbes & …, 2018 - Taylor & Francis
The 2015–2016 Zika virus (ZIKV) epidemic, resulting in> 1.5 million cases in the Americas,
emerged as a global threat to public health due to the unique findings of sexual and in utero …

Zika virus infection, reproductive organ targeting, and semen transmission in the male olive baboon

J Peregrine, S Gurung, MC Lindgren, S Husain… - Journal of …, 2019 - Am Soc Microbiol
Zika virus (ZIKV) infection in pregnant women is a serious threat to the development and
viability of the fetus. The primary mode of ZIKV transmission to humans is through mosquito …

Zika virus and reproduction: facts, questions and current management

S Epelboin, E Dulioust, L Epelboin… - Human …, 2017 - academic.oup.com
BACKGROUND Zika virus (ZIKV) is an arthropod-borne virus of the family Flaviviridae,
genus Flavivirus. ZIKV is currently the focus of an ongoing pandemic and worldwide public …

Zika Virus Infects Human Sertoli Cells and Modulates the Integrity of the In Vitro Blood-Testis Barrier Model

DN Siemann, DP Strange, PN Maharaj, PY Shi… - Journal of …, 2017 - Am Soc Microbiol
Confirmed reports of Zika virus (ZIKV) in human seminal fluid for months after the clearance
of viremia suggest the ability of ZIKV to establish persistent infection in the seminiferous …

Persistence and clinical relevance of Zika virus in the male genital tract

FA Kurscheidt, CSS Mesquita, GMZF Damke… - Nature Reviews …, 2019 - nature.com
Zika virus (ZIKV) is a re-emerging mosquito-transmitted flavivirus associated with congenital
abnormalities in newborns and with Guillain–Barré syndrome in adults. The virus can also …