Protective effect of nanoceria on cisplatin-induced nephrotoxicity by amelioration of oxidative stress and pro-inflammatory mechanisms

MA Saifi, S Sangomla, A Khurana… - Biological trace element …, 2019 - Springer
Cisplatin (CP) is one of the most important anticancer compounds with its therapeutic
usefulness in diverse types of solid cancer. However, its use is limited due to nephrotoxicity …

Gallic acid and/or cerium oxide nanoparticles synthesized by gamma-irradiation protect cisplatin-induced nephrotoxicity via modulating oxidative stress, inflammation …

M Saif-Elnasr, S El-Ghlban, AI Bayomi… - Archives of Biochemistry …, 2023 - Elsevier
Cisplatin is one of the most significant anticancer. However, its use is associated with
numerous toxicities especially nephrotoxicity. The main aim of this work was to examine the …

[PDF][PDF] Nephroprotective effect of cerium oxide nanoparticles on cyclophosphamide-induced nephrotoxicity via anti-apoptotic and antioxidant properties in BALB/c mice

M Hamzeh, FT Amiri, SY Beklar… - Marmara Pharm …, 2018 - jrespharm.com
Cyclophosphamide [CP], as alkylating agents has side effects such as nephrotoxicity.
Cerium oxide nanoparticles [nanoceria; NC], as an antioxidant, are effective at reduction …

Cerium oxide nanoparticles attenuate the renal injury induced by cadmium chloride via improvement of the NBN and Nrf2 gene expressions in rats

MM Bashandy, PhD, HE Saeed… - Toxicology …, 2022 - academic.oup.com
Abstract Background Cadmium (Cd) is a highly toxic heavy metal that adversely affects both
human and animal health. Chronic cadmium exposure causes serious kidney damage. The …

Nanoceria ameliorates doxorubicin induced cardiotoxicity: Possible mitigation via reduction of oxidative stress and inflammation

S Sangomla, MA Saifi, A Khurana, C Godugu - Journal of Trace Elements in …, 2018 - Elsevier
Doxorubicin (DOX) is one of the most commonly used anticancer drugs but its use has been
limited due to constraints of cardiotoxic side effects. The precise mechanism underlying …

Rosinidin protects against cisplatin-induced nephrotoxicity via subsiding proinflammatory and oxidative stress biomarkers in rats

SJ Gilani, MN Bin-Jumah, FA Al-Abbasi… - International Journal of …, 2022 - mdpi.com
Background: Rosinidin is a flavonoid anthocyanin pigmentation found in shrub flowers such
as Catharanthus roseus and Primula rosea. The molecular docking studies predicted that …

Protective role of zinc oxide nanoparticles in kidney injury induced by cisplatin in rats

LAA Barakat, N Barakat, MM Zakaria, SM Khirallah - Life Sciences, 2020 - Elsevier
Cisplatin used as chemotherapy for various cancers may leads to accumulation of platinum
within the kidney and disturb its function. Zinc oxide nanoparticles (ZnO-NPs) are of low …

Ameliorative impacts of polymeric and metallic nanoparticles on cisplatin-induced nephrotoxicity: a 2011–2022 review

M Davoudi, Y Jadidi, K Moayedi, V Farrokhi… - Journal of …, 2022 - Springer
Cisplatin (CDDP) is a well-known platinum-based drug used in the treatment of various
malignancies. However, the widespread side effects that this drug leaves on normal tissues …

Vitamin E mitigates cisplatin‐induced nephrotoxicity due to reversal of oxidative/nitrosative stress, suppression of inflammation and reduction of total renal platinum …

MA Darwish, AM Abo‐Youssef… - … of biochemical and …, 2017 - Wiley Online Library
Cisplatin (CP) is one of the most effective chemotherapeutic agents. Unfortunately, CP‐
induced nephrotoxicity hampered its use. This study aims to investigate the effect of vitamin …

Combined treatment of epigallocatechin gallate and Coenzyme Q10 attenuates cisplatin-induced nephrotoxicity via suppression of oxidative/nitrosative stress …

S Fatima, N Al-Mohaimeed, Y Al-Shaikh, P Tyagi… - Food and Chemical …, 2016 - Elsevier
Cisplatin (CP), a platinum based anticancer drug is used as one of the first-line therapy for
the treatment of different types of solid tumors. However, CP-induced side effects …