Background It remains unknown to what extent consensus molecular subtype (CMS) groups
and immune-stromal infiltration patterns improve our ability to predict outcomes over tumor …

Purpose Transcriptomic profiling of colorectal cancer (CRC) has led to the identification of
four consensus molecular subtypes (CMS1 to 4) that have prognostic value in stage II and III …

Abstract Background Cancer-associated fibroblasts (CAFs) contribute notably to colorectal
cancer (CRC) tumorigenesis, stiffness, angiogenesis, immunosuppression and metastasis …

Colorectal cancer (CRC) is characterized by major inter-tumor diversity that complicates the
prediction of disease and treatment outcomes. Recent efforts help resolve this by sub …

Background Colorectal cancer (CRC) consensus molecular subtypes (CMS) have different
immunological, stromal cell, and clinicopathological characteristics. Single-cell …

Background TNM staging alone does not accurately predict outcome in colon cancer (CC)
patients who may be eligible for adjuvant chemotherapy. It is unknown to what extent the …

The classification of colorectal cancer (CRC) plays a pivotal role in predicting a patient's
prognosis and determining treatment strategies. The consensus molecular subtype (CMS) …

The prognostication of colorectal cancer (CRC) has traditionally relied on staging as defined
by the Union for International Cancer Control (UICC) and American Joint Committee on …

Purpose: A number of independent gene expression profiling studies have identified
transcriptional subtypes in colorectal cancer with potential diagnostic utility, culminating in …

Background Solid tumour growth is the consequence of a complex interplay between cancer
cells and their microenvironment. Recently, a new global transcriptomic immune …