[PDF][PDF] Absence of mDazl produces a final block on germ cell development at meiosis

PTK Saunders, JMA Turner, M Ruggiu… - REPRODUCTION …, 2003 - Citeseer
Functional differentiation of spermatogonia associated with detection of c-kit positive cells
did not depend upon expression of Dazl. RBMY-positive cells (A, intermediate, B …

Nature of the Spermatogenic Arrest in Dazl −/− Mice

BHGJ Schrans-Stassen, PTK Saunders… - Biology of …, 2001 - academic.oup.com
Dazl encodes an RNA-binding protein essential for spermatogenesis. Mice that are deficient
for Dazl are infertile, lacking any formation of spermatozoa, and the only germ cells present …

DAZ family proteins exist throughout male germ cell development and transit from nucleus to cytoplasm at meiosis in humans and mice

RA Reijo, DM Dorfman, R Slee… - Biology of …, 2000 - academic.oup.com
The human DAZ gene family is expressed in germ cells and consists of a cluster of nearly
identical DAZ (deleted in azoospermia) genes on the Y chromosome and an autosomal …

Expression profiling of the developing testis in wild‐type and Dazl knockout mice

K Maratou, T Forster, Y Costa, M Taggart… - Molecular …, 2004 - Wiley Online Library
Genetic understanding of male‐factor infertility requires knowledge of gene expression
patterns associated with normal germ cell differentiation. The mouse is one of the best …

DAZL is a master translational regulator of murine spermatogenesis

H Li, Z Liang, J Yang, D Wang, H Wang… - National science …, 2019 - academic.oup.com
Expression of DAZ-like (DAZL) is a hallmark of vertebrate germ cells, and is essential for
embryonic germ cell development and differentiation, yet the gametogenic function of DAZL …

Identification of target messenger RNA substrates for the murine deleted in azoospermia-like RNA-binding protein

X Jiao, P Trifillis, M Kiledjian - Biology of reproduction, 2002 - academic.oup.com
The murine autosomal deleted in azoospermia-like protein (mDAZL) is a germ cell-restricted
RNA-binding protein essential for sperm production. Homozygous disruption of the mDAZL …

Partial rescue of the Dazl knockout mouse by the human DAZL gene

T Vogel, RM Speed, A Ross… - Molecular human …, 2002 - academic.oup.com
Y-chromosomal DAZ (deleted in azoospermia) and autosomal DAZ-like (DAZL) comprise a
gene family involved in gametogenesis. Y-chromosomal and autosomal genes only co-exist …

DAZ (Deleted In AZoospermia) genes encoie proteins located in human late spermatids and In sperm tails

B Habermann, HF Mi, A Edelmann… - Human …, 1998 - academic.oup.com
We analysed the location of proteins encoded by the DAZ (Deleted in AZoospermia) genes
in human testis tissue and in mature spermatozoa. The DAZ genes are known to be …

A gene family required for human germ cell development evolved from an ancient meiotic gene conserved in metazoans

EY Xu, FL Moore, RAR Pera - Proceedings of the National …, 2001 - National Acad Sciences
The Deleted in AZoospermia (DAZ) genes encode potential RNA-binding proteins that are
expressed exclusively in prenatal and postnatal germ cells and are strong candidates for …

Expression patterns and transcript concentrations of the autosomal DAZL gene in testes of azoospermic men

YM Lin, CW Chen, HS Sun, SJ Tsai… - MHR: Basic science …, 2001 - academic.oup.com
Abstract The DAZ (Deleted in AZoospermia) gene cluster on the Y chromosome is a strong
candidate for the azoospermia factor. The DAZ gene was derived from an autosomal …