Neuroinflammation following traumatic brain injury: take it seriously or not

R Zheng, K Lee, Z Qi, Z Wang, Z Xu, X Wu… - Frontiers in …, 2022 - frontiersin.org
Traumatic brain injury (TBI) is associated with high mortality and disability, with a substantial
socioeconomic burden. With the standardization of the treatment process, there is increasing …

Neuroimmunology of traumatic brain injury: time for a paradigm shift

YN Jassam, S Izzy, M Whalen, DB McGavern… - Neuron, 2017 - cell.com
Traumatic brain injury (TBI) is a leading cause of morbidity and disability, with a
considerable socioeconomic burden. Heterogeneity of pathoanatomical subtypes and …

The far-reaching scope of neuroinflammation after traumatic brain injury

DW Simon, MJ McGeachy, H Bayır, RSB Clark… - Nature Reviews …, 2017 - nature.com
The'silent epidemic'of traumatic brain injury (TBI) has been placed in the spotlight as a result
of clinical investigations and popular press coverage of athletes and veterans with single or …

Emerging roles for the immune system in traumatic brain injury

CA McKee, JR Lukens - Frontiers in immunology, 2016 - frontiersin.org
Traumatic brain injury (TBI) affects an ever-growing population of all ages with long-term
consequences on health and cognition. Many of the issues that TBI patients face are thought …

Dissemination of brain inflammation in traumatic brain injury

K Shi, J Zhang, J Dong, FD Shi - Cellular & molecular immunology, 2019 - nature.com
Traumatic brain injury (TBI) is recognized as a global health problem due to its increasing
occurrence, challenging treatment, and persistent impacts on brain pathophysiology. Neural …

New perspectives on central and peripheral immune responses to acute traumatic brain injury

M Das, S Mohapatra, SS Mohapatra - Journal of neuroinflammation, 2012 - Springer
Traumatic injury to the brain (TBI) results in a complex set of responses involving various
symptoms and long-term consequences. TBI of any form can cause cognitive, behavioral …

Overview of traumatic brain injury: an immunological context

D Nizamutdinov, LA Shapiro - Brain sciences, 2017 - mdpi.com
Traumatic brain injury (TBI) afflicts people of all ages and genders, and the severity of injury
ranges from concussion/mild TBI to severe TBI. Across all spectrums, TBI has wide-ranging …

Current understanding of neuroinflammation after traumatic brain injury and cell-based therapeutic opportunities

Y Xiong, A Mahmood, M Chopp - Chinese Journal of Traumatology, 2018 - mednexus.org
Traumatic brain injury (TBI) remains a major cause of death and disability worldwide.
Increasing evidence indicates that TBI is an important risk factor for neurodegenerative …

Inflammatory neuroprotection following traumatic brain injury

MV Russo, DB McGavern - Science, 2016 - science.org
Traumatic brain injury (TBI) elicits an inflammatory response in the central nervous system
(CNS) that involves both resident and peripheral immune cells. Neuroinflammation can …

The role of markers of inflammation in traumatic brain injury

T Woodcock, MC Morganti-Kossmann - Frontiers in neurology, 2013 - frontiersin.org
Within minutes of a traumatic impact, a robust inflammatory response is elicited in the injured
brain. The complexity of this post-traumatic squeal involves a cellular component …